摘要
裸鼠因其免疫缺失,可作为研究甲状腺癌的重要模型,对于研究人体甲状腺癌对药物的敏感性有很大帮助.甲状腺癌裸鼠模型的肿瘤细胞可来源于原发瘤组织,也可以来源于现有的细胞株.移植方式可分为原位移植,异位移植及尾静脉注射3种.
Nude mice can be used as important animal models to study thyroid cancer because of their deficiency of immunitv,The model is helpful study the sensitivity of thyroid cancer to drugs.The tumor cells may come from primary tumor tissue,or from the cell lines existed.There are three methods to transplant the tumor,including orthotopic transplantation,heterotopic transplantation and tail vein injection.
出处
《国际外科学杂志》
2010年第6期400-403,共4页
International Journal of Surgery
关键词
甲状腺
癌
裸鼠
动物模型
Thyroid
Cancer
Nude mice
Animal model
