期刊文献+

B超引导下羊膜腔穿刺羊水细胞检查1377例临床分析 被引量:2

Clinical analysis of 1377 cases of amniocentesis and amniocyte examination after B-ultrasound guiding
下载PDF
导出
摘要 目的:探讨B超引导下羊膜腔穿刺抽取羊水行细胞检查在产前诊断中的应用价值。方法:对1377例有产前诊断指征的孕妇在B超引导下行羊膜腔穿刺抽取羊水进行遗传学及生物化学检测,并观察母婴并发症。结果:发现染色体异常核型73例;重型α-地中海贫血4例,重型β-地中海贫血4例;B19病毒DNA(+)3例,风疹病毒RNA(+)2例,其中35例孕妇选择终止妊娠。1377例孕妇行羊膜腔穿刺均未出现严重的母婴并发症。结论:正确掌握适应证,在B超引导下行羊膜腔穿刺羊水细胞检查,并发症少,是一种安全、简便、可靠的产前诊断方法。 Objective:To approach the value in clinical application of amniocentesis and amniocyte examination after Bultrasound guiding.Methods:The genetic and biochemical exam of amniotic fluid of 1 377 pregnant women who had mark in prenatal diagnose had done amniocentesis after B-ultrasound guiding,and obverted the complication.Results:73 pregnant women with abnormal chromosome,4 cases with severeα-Mediterranean anemia,4 cases with severe β-Mediterranean anemia,3 cases with VB19-DNA(+),2 cases were with RU-RNA(+).In those abnormal cases,35 pregnant women chose to terminate gestation.Conclusion:Control exact indication for amniocentesis and amniocyte examination after Bultrasound guiding is few complication,and a safe,convenient,feasible way in prenatal diagnosis.
出处 《中国医药导报》 CAS 2010年第18期171-172,共2页 China Medical Herald
关键词 羊膜腔穿刺 羊水 产前诊断 Amniocentesis Amniotic fluid Prenatal diagnosis
  • 相关文献

参考文献8

二级参考文献14

  • 1黄瑞萍,汤韧,王亚萍,陶惠菁.经腹取羊水及脐血检查在产前诊断中的应用[J].实用妇产科杂志,1996,12(1):28-30. 被引量:3
  • 2张思仲 杜传书 等.染色体畸变综合征.医学遗传学(第2版)[M].北京:人民卫生出版社,1992.175-205.
  • 3陆国辉 马瑞娟 等.遗传咨询与产前诊断讲义[M].广州:广东省产前诊断中心,1998,3.138-144.
  • 4马金元 王伟正 等.孪生兄弟同患先天愚型[J].中华医学遗传学杂志,1999,16(4):270-270.
  • 5Tabor A, Madsen M, Obel E, et al. Norgaard-Pedersen B. Randomized controlled trial of genetic amniocentesis in 4606 lowrisk women [J]. Lancet, 1986,8493(1) : 1287-1293.
  • 6John W, Seed S. Diagnostic mid trimester amniocentesis: How safe [J]. Am J Obstet Gynecol, 2004, 191(2) :608-616.
  • 7Bombard A T, Powers J F, Carter S, et al. Procedure-related fetal losses in transplacental versus nontransplacental genetic amnioeentesis [J]. Am J Obstet Gynecol, 1995,172 (3):868- 872.
  • 8Horger E O, Finch H, Vincent V A. A single physician's experience with four thousand six hundred genetic amniocenteses [J].Am J Obstet Gynecol, 2001,185 (2) :279-288.
  • 9胡冬贵,人类单基因病,1999年,1页
  • 10朱俊真,产前实验室诊断,1992年,128页

共引文献92

同被引文献12

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部