摘要
目的 探讨四种药物治疗原发性高血压的经济成本与效果.方法 160例原发性高血压患者,随机分为贝那普利组40例、培哚普利组410例、氨氯地平组40例和尼群地平组40例,运用药物经济学的成本-效果分析进行评价.结果 四组降压总有效率比较,差异无统计学意义（均P〉0.05）;四组治疗前后症状总 积分比较,差异均有统计学意义（均P〈0.05）;培哚普利费用低于贝那普利.结论 四种药物治疗原发性高血压疗效相似,但培哚普利费用低.
Objective To investigate the economic effects in patients with primary hypertension by four kinds of treatment.Methods 160 cases with primary hypertension were randomly divided into Benazepril group（n=40）、Perindopril group（n=40）、Amlodipine group（n=40） and Nitrendipine group（n=40）,and data was evaluated with the pharmacoeconomic cost-effective analysis method.Results Hypertensive efficacy in 4 groups were not sig-nificantly different（x2=3.26,P〉0.05）;The symptom total score before treatment and after treatment was sisnifi-canfly different（a11 P〈0.05）;The SF-36 Scale after treatment in 4 groups were higher than before treatment（all P〈0.05）;The costs of pefindopril was lower than the benazepril.Conclusion Pharmacoeconomies played an important role in optimizing therapeutic scheme,guiding rational drug use and increasing economic effectiveness.
出处
《中国基层医药》
CAS
2010年第12期1625-1626,共2页
Chinese Journal of Primary Medicine and Pharmacy
