摘要
目的了解重症监护病房(ICU)患者感染病原菌分布特点及耐药情况,为控制医院感染及临床选用抗菌药物治疗提供依据。方法分析2007年10月-2008年12月入住宁夏医科大学附属医院综合ICU患者送检的各类标本中分离出的病原菌,并用纸片扩散法(K-B法)进行药物敏感试验,进行病原菌耐药性分析。结果分离出病原菌559株,标本来源中痰液阳性标本居首位,占67.4%;病原菌仍以革兰阴性杆菌为主,占51.5%,革兰阳性球菌占25.6%,真菌占总构成比12.5%;超广谱β-内酰胺酶(ESBLs)检出率55.2%,耐甲氧西林葡萄球菌(MRSA)检出率为75%。结论 ICU为医院感染高发科室,病原菌仍以革兰阴性杆菌为主,坚持细菌耐药性监测,对ICU患者感染的诊治具有重要指导意义。
Objective To investigate pathogen distribution and antimicrobial resistance in the intensive care unit（ICU） for the control of hospital infection and guidance of antibiotic clinical use of drug therapy.Methodsfrom October 2007-December 2008,a comprehensive submission of all types of pathogens were isolated from using disk diffusion method（KB method） for susceptibility testing in patients of ICU.Results559 pathogens were isolated.Sputum-positive samples ranked the first and accounted for 67.4%;pathogenic Gram-negative bacilli were still dominated,accounted for 51.5% and Gram-positive cocci accounted for 25.6%,in which methicillin-resistant grape aureus（MRSA） had a detection rate of 75%;fungi accounted for 12.5% of the total composition;ultra-extended-spectrum β-lactamases（ESBLs） had a detection rate of 55.2%,methicillin-resistant Staphylococcus aureus（MRSA） had a detection rate of 75 %.ConclusionThe rate of hospital infection was high in ICU.The pathogens were mainly Gram-negative bacteria.Bacterial resistance surveillance in ICU patients would be helpful for hospital-acquired infection diagnosis and treatment.
出处
《宁夏医科大学学报》
2010年第3期378-381,共4页
Journal of Ningxia Medical University
关键词
重症监护病房
医院感染
病原菌
耐药性
intensive care unit
nosocomial infection
pathogenic bacteria
drug resistance
