摘要
目的:了解利培酮对男性精神分裂症患者肝功能的影响。方法:对91例单一服用利培酮的住院患者在治疗前和治疗后作肝功能检测,评价肝功能的指标为谷丙转氨酶和谷草转氨酶,肝功能受损的标志为治疗后上述指标超过正常范围。结果:服用利培酮后肝功能发生异常32例(35.16%),且不受年龄与病程的影响。结论:利培酮可损害男性精神分裂症患者的肝功能,但多较轻微且易于恢复。
Objective：To investigate the difference in the effect on liver function in male schizophrenic patients treated with risperidone.Methods：Liver function tests had been measured before and after using risperidone in 91 in-patients with single risperidone use.Assessment indication of liver function tests was alanine aminotriansferase（ALT） and aspartate aminotransferase（AST）.The indication of liver function damage was that ALT or AST serum levels were higher than normal range.Results：32 patients（35.16%） manifested liver function damage after using risperidone.Liver function did not affected by both age and course.Conclusion：Risperidone caused liver function damage in schizophrenic patients.But liver function damage was slight and reversed easily.
出处
《中国民康医学》
2010年第12期1493-1493,1546,共2页
Medical Journal of Chinese People’s Health
关键词
利培酮
肝功能
男性精神分裂症
Risperidone
Male schizophrenia
Liver function
