1Linda LJ, Richard D, Donald H. Matrix metalloproteinases [ J ]. Curr Opin Chem Biol,2003,2:466 - 471.
2Fosang A J, Last K, Stanton H, et al. Generation and novel distribution of matrix metallopro teinase - derived aggrecan fragments in porcine cartilage explants [ J ]. J Bio Chem, 2000,275 : 33027 - 33037.
3Ghosh P,Smith M. Osteoarthritis,genetic and molecular mechanisms[J]. Biogerontology ,2002,1 - 2 : 85 - 88.
5Lane NE, Lian K, Nevitt MC,et al. Frizzle- related protein variants are risk factors for hip osteoarthritis [ J ]. Arthritis Rheum, 2006,4 : 1246 - 1254.
6Hardingham T. Extracellular matrix and pathogenic mechanisms in osteoarthritis[ J]. Curr Rheumatol Rep ,2008,1:30 - 36.
7Watanabe H. Aggrecan and its chondroitis sulfate in cartilage [ J]. Seikagaku ,2008,1:28 - 32.
8Keith B, Deendayal D, Hideaki N. Tissue inhibitors of metalloproteinase: evolution, structure and function [J]. Biochim Biophys Acta, 2005,1477:267 - 228.
9Neuhold LA, Klllar L, Zhao W, et al. Postnatal expression in hyaline cartilage of constitutively active human collagenase23 (MMP - 13 ) induces osteoarthritis in mouse [ J ]. J Clin Invest ,2005,107:35 -44.
10Steven RG, Mary BG. The Role of cytokines in cartilage matrix degeneration in osteoarthritis[ J]. Clin Orthop Relat R,2004 ,42:27 -40.
4Guccione AA, Felson DT, Anderson JJ, et al: Specific disease and their effects on functional limitations in elders in the Framingham Study. Am J Public Health, 1994, 84:351-358.
5Zhang N, Shi Q, Zhang X. An epidemiologic study of knee osteoarthritis. Chung-Hua Nei Ko Tsa Chih Chinese J Int Med, 1995, 34:84-87.
6Hoaglund FT, Yau ACMC, Wong WI. Osteoarthritis of the hip and other joints in southern Chinese in Hong Kong. J Bone Joint Surg Am, 1973, 55:545-547.
7Feoson DT, Naimark A, Anderson J, et al. The prevalence of knee osteoarthritis in the elderly; the Framingham Osteoarthritis Study. Arthritis Rheum, 1987,30:914-918.
8Kellgren JH, Lawrence JS. Radiological assessment of osteoarthritis. Ann Rheum Dis, 1957,16:494-501.
9Croft P, Cooper C, Wickham C, et al. Defining osteoarthritis of hip for epidemiologic studies. Am J Epidemiol, 1990, 132:514-522.
10Altman R, Asch E, Bloch D, et al. Development of criteria for the classification and reporting of osteoarthritis. Arthritis Rheum, 1986, 29:1039-1049.
5Neuhold LA,Killar L,Zhao W,et al.Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.J Clin Invest,2005; 107(1):35-44.
6Legendre F,Bogdanowicz P,Boumediene K,et al.Role of interleukin 6(IL-6)/ IL-6R-induced signal tranducers and activators of transcription and mitogen-activated protein kinase/extracellular.J Rheumatol,2005; 32(7):1307-1316.
7Brew K,Dinakarpandian D,Nagase H.Tissue inhibitors of metalloproteinases:evolution,structure and function.Biochim Biophys Acta,2000; 1477(1-2):267-283.
8McClung MR.Do current management strategies and guidelines adequately address fracture risk? Bone,2006; 38(Suppl 2):S13-S17.
9Bachmeier BE,Iancu CM,Jochum M,et al.Matrix metalloproteinases in cancer:comparison of known and novel aspects of their inhibition as a therapeutic approach.Expert Rev Anticancer Ther,2005; 5(1):149-163.
10Guo XX,Zhou JL,Xu Q,et al.Prevention of osteoporosis in mice after ovariectomy via allograft of microencapsulated ovarian cells.Anat Rec(Hoboken),2010; 293(2):200-207.