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副肿瘤性周围神经病的诊断分析 被引量：4

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摘要 副肿瘤性周围神经病（PPN）属于神经系统副肿瘤综合征（PNS）类型之一，是由于免疫反应引起的肿瘤远隔效应，其临床发病率较低，容易误诊或漏诊。诊断副肿瘤性周围神经病须首先排除肿瘤直接浸润、脑脊膜转移、放射治疗或药物化疗不良反应等因素引起的周围神经损害。笔者报告2006年3月—2009年8月首都医科大学宣武医院神经内科诊断与治疗的30例副肿瘤性周围神经病患者，并结合文献进行分析。
作者 王锁彬 贾建平
机构地区 首都医科大学宣武医院神经内科
出处 《中国现代神经疾病杂志》 CAS 2010年第3期392-394,共3页 Chinese Journal of Contemporary Neurology and Neurosurgery
关键词 副肿瘤性多发性神经病 周围神经系统疾病
分类号 R730.4 [医药卫生—肿瘤]
  • 相关文献

参考文献11

  • 1Rudnicki SA, Dalmau J. Paraneoplastic syndromes of the peripheral nerves. Curr Opin Neurol, 2005, 18:598-603.
  • 2Behin A, Psimaras D, Hoang-Xuan K, et al. Neuropathies in the context of malignancies. Curr Opin Neurol, 2008, 21:534-539.
  • 3Graus F, Delattre JY, Antoine JC, et al. Recommended diagnostic criteria for paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry, 2004, 75:1135-1140.
  • 4冯加纯.神经系统副肿瘤综合征//贾建平.神经病学.6版.北京:人民卫生出版社.2008:426-434.
  • 5Oh SJ, Gtirtekin Y, Dropcho E J, et al. Anti- Hu antibody neuropathy: a clinical, electrophysiological, and pathological study. Clin Neurophyiol, 2005, 116:28-34.
  • 6Camdessanche JP, Antoine JC, Honnorat J, et al. Paraneoplastic peripheral neuropathy associated with anti- Hu antibodies: a clinical and electrophysiological study of 20 patients. Brain, 2002, 125(Pt 1):166-175.
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二级参考文献16

  • 1Toribio- Garcia JA, Franco- Benito M, Garcia- Ruiz- de- Morales JM. Paraneopalstic optic neuritis in an unknown small cell lung carcinoma defined by CRMP-5-IgG. Arch Soc Esp Oftalmol, 2007, 82:777-780.
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  • 3Antoine JC, Honnorat J, Vocanson C, et al. Posterior uveitis, paraneoplastic encephalomyelitis and auto- antibodies reacting with developmental protein of brain and retina. J Neurol Sci, 1993, 117(1/2):215-223.
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  • 5Monstad SE, Drivsholm L, Skeie GO, et al. CRMP5 antibodies in patients with small- cell lung cancer or thymoma. Cancer hnmunol Immunother, 2008, 57:227-232.
  • 6Camdessnche JP, Lassabliere F, Meyronnet D, et al. Expression of the onconeural CV2/CRMP5 antigen in thymus and thymoma. J Neuroimmunol, 2006, 174(1/2):168-173.
  • 7Honnorat J, Cartalat-Carel S, Ricard D, et al. Onco-neural antibodies and tumour type determine survival and neurological symptoms in paraneoplastic neurological syndromes with Hu or CV2/CRMP5 antibodies. J Neurol Neurosurg Psychiatry, 2009, 80:412-416.
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共引文献1

同被引文献15

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二级引证文献5

中国现代神经疾病杂志
2010年 第3期

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