摘要
目的了解成都市新生儿百日咳、白喉、破伤风胎传抗体的水平及其变化情况。方法在4个区县对142名新生儿的脐血进行百日咳、白喉、破伤风抗体水平调查。结果百日咳抗体达到保护水平的率为1.41%,明显低于1988年的抗体水平(χ2=5.80,P<0.05);白喉、破伤风抗毒素平均滴度为0.3750和0.3537,其抗体达到保护水平的率分别为48.59%和52.11%,明显高于1988年的抗体水平(χ2=25.29,P<0.05;χ2=63.49,P<0.05)。结论该市新生儿百日咳、白喉、破伤风胎传抗体水平达不到有效的保护,应重视新生儿父母、与年龄较小儿童接触和其他适合接种白破疫苗的成人的免疫接种,以保护新生儿免受此类疾病的感染。
Objective To understand the antibody levels of pertussis,diphtheria and tetanus in newborns in Chengdu.Methods A total of 142 cord serum samples of newborns from 4 districts and counties were used for antibody level detections of pertussis,diphtheria and tetanus.Results The protection rate of pertussis antibody was 1.41%,which was lower than the level in 1988（χ2=5.80,P0.05）.The GMTs of diphtheria and tetanus were 0.375 0 and 0.353 7 with the protection rates of 48.59% and 52.11%,which were higher than the levels in 1988（χ2=25.29,P0.05;χ2=63.49,P0.05）.Conclusion The antibody levels of pertussis,diphtheria and tetanus in newborns in Chengdu could not provide effective protection.It is recommended that the parents of newborns,young children and other eligible adults receive DPT vaccination to protect newborns from these diseases.
出处
《预防医学情报杂志》
CAS
2010年第6期479-481,共3页
Journal of Preventive Medicine Information
关键词
新生儿
抗体
百日咳
白喉
破伤风
Newborn
Antibody level
Pertussis
Diphtheria
Tetanus
