摘要
目的观察利巴韦林联合匹多莫德治疗手足口病的临床疗效。方法将64例手足口病患儿随机分为观察组和对照组各32例,所有患儿均口服利巴韦林颗粒,观察组同时加用匹多莫德颗粒。观察两组疗效。结果观察组的显效率、总有效率均优于对照组(P<0.01),观察组总病程、退热时间、手足皮疹及口腔溃疡消失时间均短于对照组。结论在利巴韦林抗病毒治疗基础上联合匹多莫德,可明显提高小儿手足口病临床疗效,缩短病程,且无明显毒副作用,值得临床推广。
Objective To observe the therapeutic effect of ribavirin combined with pidotimod in the treatment of hand-footmouth disease（HFMD）in children.Methods 64 children with HFMD who orally took ribavirin granules were randomly divided into two groups.The observation group（n = 32）took pidotimod orally at the same time.The therapeutic effects of the two groups were observed.Results The excellence rate and the total effective rate of the treatment group were significantly better than those of the control group（P 0.01）.The total course of disease,antipyretic and the disappearing time of hand-foot rash and mouth ulcers in the observation group were shorter than those of the control group.Conclusion The combination of ribavirin and pidotimod in the treatment of children with HFMD can improve the clinical therapeutic effect,shorten the course of disease with no obvious toxic and side effects.
出处
《白求恩军医学院学报》
2010年第3期165-167,共3页
Journal of Bethune Military Medical College
