摘要
目的 探讨丹参对颈椎管狭窄症术后脊髓缺血再灌注损伤的治疗效果.方法 回顾性分析5年来我院收治的64例颈椎管狭窄症施行颈椎后路单开门术的患者,随机分为丹参组（31例）及对照组（33例）.按JOA标准评定疗效.结果 丹参组术前JOA评分平均为（8.8±2.6）分,术后2周JOA评分平均为（13.7±2.4）分,改善率为（61.5±2.9）%.对照组术前JOA评分平均为（9.1±2.2）分,术后2周JOA评分平均为（13.4±2.3）分,改善率为（60.5 ±2.2）%.丹参组JOA评分改善率明显优于对照组（P〈0.05）.结论 丹参时脊髓缺血再灌注损伤有保护作用,能有效促进术后脊髓功能恢复.
Objective To investigate the effect of salvia mihiorrhiza on spinal cord ischemia reperfusion injury after surgical treatment in patients with cervical canal stenosis. Methods Retrospective analysis of 64 cases had cervical canal stenosis in the last 5 years in our hospital. Sixty-four cases were randomly divided into the salvia mihiorrhiza group（31 cases）and the control group（33 cases）. The therapeutic effect was assessed using JOA grade system. Results In the salvia mihiorrhiza group,the JOA average score was 8. 8 ±2. 6 before surgical treatment, after two weeks of surgical treatment it was 13. 7 ± 2. 4. The JOA improvement ratio was （61. 5 ± 2. 9） % . In the control group,the JOA average score was 9. 1 ±2. 2 before surgical treatment,after two weeks of surgical treatment it was 13. 4 ± 2. 3. The JOA improvement ratio was （60. 5 ± 2.2）% .The JOA improvement ratio in the salvia mihiorrhiza group was significantly higher than that in the control group （P 〈 0. 05） . Conclusions Salvia mihiorrhiza has protective effect on spinal cord ischemia reperfusion injury.
出处
《中国综合临床》
2010年第6期628-630,共3页
Clinical Medicine of China
关键词
丹参
脊髓缺血再灌注损伤
Salvia mihiorrhiza
Spinal cord ischemia reperfusion injury
