摘要
目的了解基层医院重症监护病房(ICU)鲍曼不动杆菌感染的分布特点及其耐药谱变化。方法采用回顾性调查方法 ,对浙江省仙居县人民医院2005年1月~2007年12月ICU送检样品中分离得到的239株鲍曼不动杆菌药敏试验及感染患者的临床资料进行统计分析。结果 2005-2007年鲍曼不动杆菌检出率分别为9.04%,18.76%,17.75%;样品主要来源于痰(235/239,98.33%);年龄〉60岁患者占74.48%;患者平均住院时间中位数为23 d;鲍曼不动杆菌对13种抗菌药物的耐药率逐年增高。结论 ICU患者中鲍曼不动杆菌检出率、耐药率呈逐年上升趋势。ICU应严格执行准入制度,慎重合理使用三、四代头孢及碳青霉烯类抗菌药物,加强手卫生及消毒隔离,减少耐药菌株的产生和传播。
Objective To identify the distribution characteristics and drug resistance of Acinetobacter baumannii in the ICU of a local hospital.Methods Two hundred and thirty-nine strains of Acinetobacter baumannii were isolated from January 2005 to December 2007.The drug susceptibility testing and clinical data were retrospectively analyzed.Results The strains were mainly isolated from sputum specimeins(235/239,98.33%).The positive rates were 9.04%,18.76 % and 17.75 % respectively for the year of 2005,2006 and 2007.74.48% of the strains were isolated from patients older than 60 years.The median length of hospitalization was 23 days.The drug resistance rates to 13 clinical used antibiotics increased year by year.Conclusion There was an increasing trend in detection rate and drug resistance strains of Acinetobacter baumannii from ICU patients.The results suggested the necessary of strict standards of ICU hospitalization,reasonable application of antimicrobial agents,complete disinfection and hand hygiene of medical staff.
出处
《中国预防医学杂志》
CAS
2010年第6期608-609,共2页
Chinese Preventive Medicine
关键词
重症监护病房
鲍曼不动杆菌
耐药性
Intensive care unit(ICU)
Acinetobacter baumanni
Drug resistance