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肝门部胆管癌外科治疗25年的历程 被引量:22

Management of hilar cholangiocarcinoma: review of a 25-year experience
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摘要 1989年,国内首次报道肝门部胆管癌以来,该病的治疗作为跨世纪的热点问题已逐渐深入。但是,存在的争议仍然较多,距最后解决问题仍有差距。 Hilar cholangiocarcinoma has received great attention in the past 25 years because of its rising prevalence. However, the results of surgical treatment of hilar cholangiocareinoma are still unsatisfactory. A series of studies on eholangiocarcinoma, both clinical and experimental, were conducted in the Research Institute of Hepatobiliary Surgery of PLA. Detailed elinicopathological research revealed the characteristics of nerve involvement and metastasis of bile duct cancer, which may be responsible for the high recurrence after surgical removal. Hepatitis C virus may be one of the causal factors of bile duct cancer in China. Clinically, of the 402 patients with hilar eholangioearcinoma, 51.5% of the resections were found to be R0. The 5-year survival rate was 33. 3% and the morality rate was 0.3%. For those high-risk patients with jaundice, when resection of the hepatic artery was found to be necessary, an arterialportal venous shunt was constructed with satisfactory results. However, the best approach to treat hilar cholangiocarcinoma still needs further investigation.
作者 黄志强
出处 《中华消化外科杂志》 CAS CSCD 2010年第3期161-164,共4页 Chinese Journal of Digestive Surgery
关键词 胆管肿瘤 肝门 外科手术 治疗 Cholangiocarcinoma, hilar Surgical procedures, operative Therapy
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