摘要
目的观察祛淤生新冲洗液术后鼻腔冲洗对鼻内镜手术疗效的影响。方法鼻内镜手术治疗的120例2型慢性鼻窦炎患者,术后随机分为2组。治疗组63例,术后应用祛淤生新冲洗液鼻腔冲洗,每日1次;对照组57例,术后应用0.9%生理盐水鼻腔冲洗,每日1次。均连续应用4周,然后比较2组术腔愈合情况。结果治疗组1期、2期、3期术腔开始上皮化时间分别为8.93±1.90d,10.0±2.17d,10.92±1.81d;对照组分别为10.67±2.31d,12.58±3.02d,13.8±2.10d,差异有统计学意义。术后第4周及8周,治疗组和对照组疗效分别为76.2%、85.7%及57.9%、70.2%,差异有统计学意义。术后第8周,治疗组及对照组术腔粘连发生率分别为1.6%和12.3%,差异有统计学意义。结论鼻内镜术后应用祛淤生新冲洗液鼻腔冲洗,能缩短术腔上皮化时间,降低术腔粘连发生率,提高治愈率。
Objective To observe the therapeutic effect of postoperating nasal douching with Stasis-Dispelling the New- Engendering Decoction （SDNED） among patients with chronic sinusitis treated by endoscopic sinus surgery based on a clinical trial. Methods Included in this study were 120 cases with chronic sinusitis and/or nasal polyps treated by endoscopic sinus surgery （ESS）, randomly divided into two groups after the operation, i.e. 63 cases in treating group （TG） received daily nasal douching with SDNED and 57 cases in controlling group （CG） received daily nasal douching in the same way with 0.9% normal saline lasted for 4 weeks for all of them. Then, a comparative analysis was made to evaluate the difference in healing status in operative cavity between the two groups. Results The mean periods of epithelization at stage one, two and three in the operative cavity were 8.93±1.90, 10.0±2.17 and 10.92±1.81 d for cases in TG, and they were 10.67±2.31, 12.58±3.02 and 13.8±2.10 d for those in CG respectively, with marked statistical significance （P〈0.05）. The effecttive rates as evaluated at the 4^th and 8^th weeks were 76.2% and 85.7% in TG, whil these were 57.9% and 70.2% in CG respectively, also with marked statistical significance （P〈0.05） between them. Furthermore, the incidence of postoperative adhesion in operative cavity was 1.6% in TG and it was 12.3% in CG at the 8th week after operation （P〈0.05）. Conclusion Nasal douche with has important clinical significances to improve the healing rate of sinustis and ventilation function and decrease conglutination rate.
出处
《中国中西医结合耳鼻咽喉科杂志》
2010年第3期137-138,共2页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
关键词
慢性鼻窦炎
鼻内镜手术
祛瘀生新冲洗液
鼻腔冲洗
术腔愈合
Chronic sinusitis
Endoscopic sinus surgery
Stasis-Dispelling the New-Engendering Decoction
Nasal douche
Operative area healing
