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罗格列酮与胰岛素信号传递中的IRS-2、FOXO1及胰岛素抵抗关系的研究进展 被引量：2

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作者 罗静思 夏宁
机构地区 广西医科大学第一附属医院代谢糖尿病中心
出处 《广西医学》 CAS 2010年第5期592-595,共4页 Guangxi Medical Journal
基金 广西科学研究与科技攻关课题(桂科攻0472002-27)
关键词 罗格列酮 胰岛素抵抗 IRS-2 FOXO1
分类号 R977.15 [医药卫生—药品]
  • 相关文献

参考文献18

  • 1Jia DM,Otsuki M.Troglitazone stimulates pancreatic growth in normal rats[J].Pancreas,2002,24(3):303-312.
  • 2Richardson H,Campbell C,Smith A,et al.Effects of rosiglitazone and metformin on pancreatic beta cell gene expression[J].Diabetologia,2006,49(4):685-696.
  • 3Rafacho A,Cestari TM,Taboga SR,et al.High doses of dexamethasone induce increased beta-cell proliferation in pancreatic rat islets[J].Am J Physiol Endocrinol Metab,2009,296(4):E681-E689.
  • 4Grommes C,Landreth GE,Heneka MT.Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists[J].Lancet Oncol,2004,5(7):419-429.
  • 5Lalloyer F,Vandewalle B,Percevault F,et al.Peroxisome proliferator-activated receptor -α improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets[J].Diabetes,2006,55(6):1 605-1 613.
  • 6Wang MC,Bohmann D,Jasper H.JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling[J].Cell,2005,121(1):115-125.
  • 7Adam D,Julie M,Gemma V,et al.Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptor[J].Molecular and Cellular Bioliogy,2007,27(10):3 569-3 577.
  • 8Hennige AM,Ozcan U,Okada T,et al.Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells[J].Am J Physiol Endocrinol Metab,2005,289(2):337-346.
  • 9Jason C,O'Connor CL,Christopher B,et al.Type 2 diabetes impairs insulin receptor substrate-2-mediated type 2 diabetes-a matter of beta-cell life and death[J].Science,2005,307(5 708):380-384.
  • 10Escribano O,Arribas M.Valverde AM,et al.IRS-3 mediates insulin-induced glucose uptake in differentiated IRS-2(-/-)brown adipoeytes[J].Mol Cell Endocrinol,2007,268(1-2):1-9.

同被引文献22

  • 1Kubota T, Kubota N, Kumagai H, et al. Impaired insulin signaling in endothelial cells reduces insulin- induced glucose uptake by skeletal muscle [ J ]. Cell Metabolism, 2011, 13(3) :294.
  • 2Inoguchi T, Li P, Umeda F, et al. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD (P) H oxidase in cultured vascular cells [ J ]. Diabetes ,2000,49 ( 11 ) : 1939.
  • 3Whiteside C I. Cellular mechanisms and treatment of diabetes vascular complications converge on reactive oxygen species [ J 1- Current Hypertension Reports,2005, 7(2) :148.
  • 4Sameer S. Kulkarni,Firoozeh Salehzadeh,Tomas Fritz,Juleen R. Zierath,Anna Krook,Megan E. Osler.Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus[J].Metabolism.2012(2)
  • 5Nynke J. van der Zijl,Erik H. Serné,Gijs H. Goossens,Chantalle C.M. Moors,Richard G. IJzerman,Ellen E. Blaak,Michaela Diamant.Valsartan-induced improvement in insulin sensitivity is not paralleled by changes in microvascular function in individuals with impaired glucose metabolism[J].Journal of Hypertension.2011(10)
  • 6Bart F. Geerts,Marloes G.J. van Dongen,Baukje Flameling,Matthijs M. Moerland,Marieke L. de Kam,Adam F. Cohen,Johannes A. Romijn,Cindy C. Gerhardt,Joris Kloek,Jacobus Burggraaf.Hydrolyzed Casein Decreases Postprandial Glucose Concentrations in T2DM Patients Irrespective of Leucine Content[J].Journal of Dietary Supplements.2011(3)
  • 7田秀红,刘鑫峰,闫峰,王卫民,尹汝龙.苦荞麦的药理作用与食疗[J].农产品加工（下）,2008(8):31-33. 被引量：24
  • 8蔡鹰,魏群利,陆晓和.回心草对脐静脉内皮细胞的保护作用及对分泌一氧化氮和一氧化氮合酶的影响[J].中国实验方剂学杂志,2009,15(7):79-82. 被引量：10
  • 9明志红,肖伟,黄雁玲.二甲双胍联合用药治疗2型糖尿病的疗效观察[J].当代医学,2010,16(9):51-51. 被引量：16
  • 10郑华,戈延茹.改善胰岛素抵抗的中药活性成分及其作用机制研究进展[J].中国中药杂志,2010,35(4):531-535. 被引量：21

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二级引证文献29

广西医学
2010年 第5期

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