摘要
目的探讨甲状腺功能亢进(甲亢)患者血凝状态。方法检测41例初诊甲亢患者(甲亢组)血浆纤维蛋白原(Fib)、APTT及D-二聚体(D-D)水平,以甲状腺功能正常体检者作为对照组。结果甲亢组血浆APTT水平显著低于对照组[(23.8±4.5)svs.(34.7±5.6)s],Fib、D-DI水平显著高于对照组[(2.8±0.8)g/Lvs.(2.5±0.5)g/L],[(0.45±0.16)g/Lvs.(0.22±0.13)g/L](P<0.05)。结论甲亢患者处于相对高凝状态,此增加了血栓形成风险。
Objective To investigate the coagulation status of patients with hyperthyroidism.Methods The activated partial thromboplastin time（APTT）,fibrinogen（Fib）and D-dimer（D-D）levels were detected in 41 patients with newly diagnosed hyperthyroidism,which were compared to those in the healthy persons with normal thyroid function.Results Plasma APTT in hyperthyroid patients was significantly lower than that in the controls[（23.8±4.5）s vs.（34.7±5.6）s]（P0.05）.Plasma levels of Fib and D-D in hyperthyroid patients were significantly higher than those in the controls[（2.8±0.8）g/L vs.（2.5±0.5）g/L and（0.45±0.16）g/L vs.（0.22±0.13）g/L]（P0.05）.Conclusion Patients with hyperthyroidism are in a relatively hypercoagulable state,which increases the risk of thrombosis.
出处
《江苏医药》
CAS
CSCD
北大核心
2010年第11期1264-1265,共2页
Jiangsu Medical Journal
