期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

微重力环境下Notch信号对神经干细胞分化的影响 被引量：3

The effects of Notch signal pathway on the differentiation of neural stem cells under microgravity
下载PDF
导出
摘要 基于微重力条件下神经干细胞的分化情况,结合Notch信号通路对神经干细胞分化的影响,论述模拟微重力对神经干细胞分化产生影响的可能分子机制。 Based on the differentiation situation of neural stem cells under microgravity,combining with the influences of Notch signal pathway on the differentiation of neural stem cells,this paper discusses possible molecular mechanism of simulated microgravity on the differentiation of neural stem cells.
作者 王晓阳 安宜
机构地区 北京理工大学生命科学与技术学院
出处 《长春大学学报》 2010年第6期36-37,共2页 Journal of Changchun University
基金 "863"计划重大项目[2008AA××××××秘密]
关键词 NOTCH信号通路 神经干细胞 模拟微重力 分化 Notch signal pathway neural stem cell simulated microgravity differentiation
分类号 Q189 [生物学—神经生物学]
  • 相关文献

参考文献6

  • 1Fiuza UM, Arias AM. Cell and molecular biology of Notch [ J ]. Endocrinol, 2007, 194 (3) : 459 - 474.
  • 2Mancini S J, Mantei N, Dumortier A, et al. Jaggedl-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation[J]. Blood, 2005, 105(6) :2340-2342.
  • 3Weinmaster G. Notch signal transduction: a real rip and more[ J]. Curr Opin Genet Dev, 2000, 10(4) :363 -369.
  • 4Danald C. D. , Cooper C. R. , Harris-Hooker S. , et al. Cytoskeletal organization and cell motility correlates with metastatic potential and state of differentiation in prosta te cancer[ J ]. Cell Molecular Biology, 2001,47 (6) : 1033 - 1038.
  • 5Xu A, Haines N, Dlugosz M, et al. In vitro reconslitution of the modulation of Drosophila Notch-ligand binding by Fringe[ J ]. Biol Chem,2007, 282(48) :35153 -35162.
  • 6Miele L. Notch signaling [J]. Clin Cancer Res, 2006, 12(4) : 1074 -1079.

同被引文献54

  • 1李天志,刘长庭,李向红,杜显锋,汪德生,袁明,李志利,张伟霞.模拟失重对大鼠肺组织NF-κB表达的影响[J].解放军医学杂志,2006,31(10):997-998. 被引量：6
  • 2Aoki K, Ogawa Y- Iwasaki K, et al. Approach to elucidating the influences and factors affecting circulation system in humans in space environment[J]. Nihon Eiseigaku Zasshi, 2011, 66(3): 568-572.
  • 3Thirsk R, Kuipers A, Mukai C, et al. The space-flight environment: the International Space Station and beyond[J]. CMAJ, 2009, 180(12): 1216-1220.
  • 4Pietsch J, Bauer J, Egli M, et al. The effects of weightlessness on the human organism and mammalian cells[J]. Curt Mol Med, 2011, 11(5): 350-364.
  • 5Chandler D. Weightlessness and microgravity[J]. Phys Teacher, 1991, 29(S): 312-313.
  • 6White KL, Rider DN, Kalli KR, et al. Genomics of the NF- K B signaling pathway: hypothesized role in ovarian cancer[J]. Cancer Causes Control, 2011, 22(5): 785-801.
  • 7Kanematsu M, Yoshimura K, Takaoki M, et al. Vector-averaged gravity regulates gene expression of receptor activator of NF- kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway[J]. Bone, 2002, 30(4): 553-558.
  • 8Ulbrich C, Westphal K, Baatout S, et al. Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity[J]. J Cell Biochem, 2008, 104(4): 1324- 1341.
  • 9Wise KC, Manna SK, Yamauchi K, et al. Activation of nuclear transcription factor-kappaB in mouse brain induced by a simulated microgravity environment[J]. In Vitro Cell Dev Biol Anita, 2005, 41(3/4): 118-123.
  • 10Sharma CS, Sarkar S, Periyakaruppan A, et al. Simulated microgravity activates apoptosis and NF-kappaB in mice testis[J]. Mol Cell Biochem, 2008, 313(1/2): 71-78.

引证文献3

二级引证文献8

长春大学学报
2010年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部