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重症监护病房患者的血糖控制目标:越严格越好吗? 被引量:2

Target of blood glucose control in the critically ill patients: The tighter, the better?
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摘要 近年来,有关重症监护病房(ICU)患者高血糖处理的问题受到了越来越多的关注。流行病学资料显示,ICU患者中严重的高血糖通常伴有更高的死亡率和合并症。一些关于ICU患者强化血糖控制的大规模临床试验相继开展,但是研究结论却不完全相同。最新的临床研究证据提示,ICU患者的血糖控制目标一般应该是7.8~10mmol/L。然而,临床工作中应该注意个体化原则,既要关注高血糖的危害,又要避免低血糖的风险。 The management of hyperglycemia in the intensive care unit (ICU) patients has been concerned in recent years. Epidemiological data show that the occurrence of severe hyperglycemia is associated with increased mortality and morbidity in ICU patients. Several large scale trials about intensive glycemic control in the critically ill patients were carried out, but reached disparate conclusions. Based on the latest clinical research evidences, the optimal target range of blood glucose level in ICU patients seems to be 7.8-10 mmol/L. However, the target should be individualized in clinical practice. Both hyperglycemia and hypoglycemia should be carefully avoided.
作者 田勍 洪天配
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2010年第6期440-443,共4页 Chinese Journal of Endocrinology and Metabolism
关键词 重症监护病房 血糖控制 高血糖症 低血糖症 Intensive care unit Blood glucose control Hyperglycemia Hypoglycemia
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  • 1McCowen KC,Malhotra A,Bistrian BR.Stress-induced hypeglycemia.Crit Care Clin,2001,17:107-124.
  • 2Capes SE,Hunt D,Malmberg K,et al.Stress hyperglycemia and increased risk of death after myocardial infarction in patients with and without diabetes:a systematic overview.Lancet,2000,355:773-778.
  • 3Capes SE,Hunt D,Malmberg K,et al.Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients:a systematic overview.Stroke,2001,32:2426-2432.
  • 4Krwinsley JS.Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients.Mayo Clin Proe,2003,78:1471-1478.
  • 5Gale Sc,Sicoutris C,Reilly PM,et al.Poor glycemie control is asseciated with increased mortality in critically ill trauma patients.Am Surg,2007,73:454-460.
  • 6Ray KK,Soshasai SR,Wijesuriya S,et al.Effect of intensive control of gluoose on cardiovascular outcomes and death in patients with diabetes mellitus:n meta-analysis of randomiscd controlled trials.Lancet,2009,373:1765-1772.
  • 7Van den Berghe G,Wouters P,Weekers F,et al.Intensive insulin thempy in critically ill patients.N Engl J Med,2001,345:1359-1367.
  • 8Van den Berghe G,Wilmer A,Hermans G,et al.Intensive insulin therapy in the medical ICU.N Engl J Med,2006,354:449-461.
  • 9Grey NJ,Perdrizet GA.Reduction of nosocomial iofeetions in the surgical intensive-care unit by strict rlyesmic control.Endecr Pract,2004,10(Suppl 2):46-52.
  • 10Krinsley JS.Effect of an intensive rlucose management protocol on the mortality of critically ill adult patients.Mayo Clin Proc,2004,79:992-1000.

二级参考文献69

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  • 1Katherine E, Raffaele M, Dsrio G. Stress hyperglycemia, in- flammation, and cara - diovascular event. Diabetes Care, 2003,26(5) : 1560 - 1561.
  • 2刘克梅,韩晓芳,戴武,叶军,刘玲.胰岛素泵治疗2型糖尿病疗效观察[J].安徽医学,2007,28(6):539-540. 被引量:9
  • 3Carroll MF, Burge MR, Schade DS, Severe hypoglycemia in adults. Rev Endocr Metab Disord, 2003,4: 149-157.
  • 4Mac Leod KM. Hypoglycaemia in diabetes. Clin Med, 2004, 4: 301-307.
  • 5Gruden G, Barutta F. Severe hypoglycemia and cardiovascular disease incidence in type 1 diabetes. The EURODIAB Prospective Complications Study. Diabetes Care, 2012,35:604-1598.
  • 6Gosmanov NR, Szoke E. Role of the decrement in intraislet insulin for the glucagon response to hypoglycemia in humans. Diabetes Care, 2005,28 : 1124-1131.
  • 7Mc Garraugh G. Alarm characterization for a continuous glucose monitor that replaces traditional blood glucose monitoring. J Diabetes Sci Teehnol, 2010,4:49-56.
  • 8Peyrot M. Patient-reported outcomes for an integrated real-time continuous glucose monitoring/insulin pump system. Diabetes Technol Ther, 2009,11:57-62.
  • 9Djakoure Platonoff C, Radermercker R, Reach G. Accuraey of the continuous glucose monitoring system in inpatient and outpatient conditions. Diabetes Metab, 2003,29:159.
  • 10Korzon-Burakowska A, Hopkins D, Matyka K, et al. Effect of glycemic control on protective responses against hypoglycemia in type 2 diabetes. Diabetes Care, 1998,21:283-290.

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