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腔隙性脑梗死患者血清总胆固醇与高密度脂蛋白胆固醇比值的临床意义 被引量：4

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摘要 目的探讨血清总胆固醇与高密度脂蛋白胆固醇比值(TC/HDL-C)与老年腔隙性脑梗死(LI)发病之间的相关性。方法利用全自动生化仪监测71例老年腔隙性脑梗死患者静脉血脂中的总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)及TC/HDL-C比值,并与健康对照组进行比较。结果 (1)LI组TC、LDL-C水平均高于对照组(P<0.05,P<0.01),HDL-C及TG水平与对照组相比差异无统计学意义(P>0.05)。(2)LI组的TC/HDL-C为4.38±1.29,对照组为3.79±0.81,LI组明显高于对照组(P<0.01),logistic回归分析显示,影响LI的危险因素有TC/HDL-C、LDL-C及收缩压。结论血脂紊乱与LI的发生有密切相关性,其中TC/HDL-C较单项血脂更具敏感性,是腔隙性脑梗死的独立危险因素。
作者 刘秦
机构地区 广州医学院第一附属医院神经内科
出处 《广东医学》 CAS CSCD 北大核心 2010年第12期1562-1564,共3页 Guangdong Medical Journal
关键词 腔隙性脑梗死 血脂 总胆固醇 高密度脂蛋白胆固醇
分类号 R446.112 [医药卫生—诊断学]
  • 相关文献

参考文献10

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二级参考文献25

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共引文献16

同被引文献35

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  • 10Gerhard GT, Duell PB. Homocysteine and atheroselerosis [ J]. Curt Opin Lipidol, 1999,10(5) :417-428.

二级引证文献16

广东医学
2010年 第12期

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