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艾滋病高效抗反转录病毒治疗并发高脂血症的研究进展 被引量：10

Advances in study on HAART-associated hyperlipidemia in AIDS patients
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摘要 高效抗反转录病毒疗法(HAART)使艾滋病病毒(HIV)感染者的病死率明显下降,极大地提高了艾滋病(AIDS)病人的生存率。随着治疗时间的延长,病人长期服用抗病毒药物引起的代谢异常日益受到重视,其中HAART相关的高脂血症因可能使心血管病风险升高而备受关注。该文就HAART治疗并发的高脂血症的流行病学、发病机制及干预治疗策略的相关进展进行了阐述。 The mortality of patients infected with HIV has decreased dramatically after highly active antiretroviral therapy （HAART）,resulting in major improvement of survival of HIV-infected individuals. However,the metabolic abnormalities resulting from long term administration of ARV medications have aroused increasing attention,and hyperlipidemia in HIV-positive patients receiving HAART has represented a major concern,since it may cause a significant risk to cardiovascular disease. The advance in epidemiology,pathogenesis and diagnosis of hyperlipidemia in HIV-positive patients receiving HARRT,as well as its treatment,are discussed in this paper.
作者 王凌航 赵红心 毛羽
机构地区 北京地坛医院感染性疾病诊疗中心
出处 《中国艾滋病性病》 CAS 2010年第3期319-322,326,共5页 Chinese Journal of Aids & STD
基金 "艾滋病和病毒性肝炎等重大传染病防治"科技重大专项 "十一五"计划第一批课题---中医药防治重大传染病项目--艾滋病机会性感染及减少HAART毒副作用的中医药治疗方案/方法研究(课题编号:2008zx10005 -003)~~
关键词 艾滋病 高效抗反转录病毒疗法 高脂血症 AIDS Highly active antiretroviral therapy （HAART） Hyperlipidemia
分类号 R512.91 [医药卫生—内科学]
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参考文献23

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中国艾滋病性病
2010年 第3期

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