摘要
目的探讨麝香保心丸联合硝酸异山梨醇酯片(消心痛)治疗冠心病心绞痛的疗效及其对血脂的影响。方法选取冠心病心绞痛患者100例,随机分为两组,治疗组口服麝香保心丸,每次2粒,每日3次,消心痛每次5 mg,每日3次,对照组50例单用硝酸异山梨醇酯片(消心痛)治疗。每次10 mg,每日3次。两组疗程均为2月。观察临床疗效、心电图、治疗前后血脂变化情况。结果治疗组临床症状改善及心电图改善率、血脂改善情况明显优于对照组(P<0.05)。且没有明显的毒副作用,值得大力推广。结论麝香保心丸联合消心痛是一种安全、有效的治疗冠心病心绞痛的药物。联合应用比单用消心痛更有效。
Objective The aim of this study was to observe the therapeutic effects and lowering blood lipid effects of heart-protecting Musk fills(HMF) with combination of iscaorbide dinitratr(cedocard) in treating the coronary-angina pectoris.Methods We observed 100 cases that suffered from coronary heart disease who were divided into two groups randomly: treatment group(50 cases) were treated with HMF(two pills,third daily by oral) and isosorbide dinitratr(5 mg,third daily by oral),in control group(50 cases) were treated in isosorbide dinitratr(10 mg,third daily by oral).All cases with 2 months course of treatment.And observe the clinical therapeutic effects,electrocardiogram,blood-fat changing.Results HMF could significantly improve the clinical symptoms,enhance the improvement rate of electrocardiogram and reduce the blood-fat level compare to the control group(P〈0.05).Moreover,HME was no significant toxic and side reactions,therefore,to be worth using.Conclusions Musk fills(HMF) is a safety and effective drug for the treatment of coronary angina pectoris,and combination with iscaorbide dinitratr more effective than iscaorbide dinitratr single.
出处
《辽宁医学院学报》
CAS
2010年第3期212-213,230,共3页
Journal of Liaoning Medical University (LNMU) Bimonthly