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分化抑制蛋白-1在甲状腺乳头状癌中的表达及其意义 被引量:1

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摘要 目的探讨分化抑制蛋白-1(Id-1)在甲状腺乳头癌中的表达及其意义。方法随机选择45例甲状腺乳头状癌、30例结节性甲状腺肿伴乳头状增生、7例滤泡腺瘤和15例正常甲状腺组织,采用免疫组化染色SP法检测Id-1在上述疾病中的表达。结果 Id-1的检测结果为"+"、"++"、"+++"的阳性率在甲状腺乳头状癌中分别为8.88%、31.11%、57.77%;结节性甲状腺肿伴乳头状增生中为23.33%、30.00%、40.00%;滤泡腺瘤中为28.57%、57.14%、14.28%;正常甲状腺组织中为73.33%、0、0。采用秩和检验,P<0.01。结论 Id-1在甲状腺乳头状癌中呈高表达,有望作为病理诊断的参考指标。
出处 《福建医药杂志》 CAS 2010年第3期97-99,共3页 Fujian Medical Journal
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