摘要
目的探讨肌酸激酶同功酶(CK-MB)、肌钙蛋白I(cTnI)和C反应蛋白(CRP)联合检测时对病毒性心肌炎的诊断意义。方法对66例病毒性心肌炎患儿、60例疑似心肌炎儿童及60例正常儿童进行CK-MB、cTnI和CRP检测。结果 VMC组的三项检测指标阳性率均显著高于正常对照组(P<0.01),VMC组CK-MB与疑似心肌炎组比较,无显著差异(P>0.05)。三指标对VMC诊断的特异性由高到低依次是:CRP(79.2%)、cTnI(54.2%)、CK-MB(51.7%),敏感性依次为cTnI(86.3%)、CK-MB(78.8%)、CRP(69.7%)。三指标联合检测时,特异性可提高到94.2%。结论 CK-MB、cTnI和CRP三项指标联合检测可提高对VMC的诊断特异性,有助于病毒性心肌炎的诊断。
Objective To study the diagnostic significance of combined detection of creatine kinase isoenzyme （ CK - MB）, tropanin I （eTnI） and C - reactive protein （CRP） in patients with viral myocarditis. Methods CK - MB, cTnI and CRP were detected in 66 pediatric patients with viral myocarditis, 60 pediatric patients with suspected myocarditis and 60 normal children. Results VMC group＇s three indicators of the positive test was significantly higher than the control group （ P 〈 0.01 ）, VMC group CK - MB and suspected myocarditis group, no significant difference （ P 〉 0.05 ）. Three indicators of the VMC is the specificity of diagnosis in order were： CRP （79.2%）, eTnI （54.2%）, CK- MB （ 51.7 % ）, followed by the sensitivity of cTnI （ 86.3 % ）, CK - MB （78.8 % ）, CRP （ 69.7 % ）. When the three markers in the specificity increases to 94.2%. Conclusion The combined determination of CK - MB, cTnI and CRP can improve the diagnostic specificity of VMC and it is helpful for the diagnosis of VMC.
出处
《临床和实验医学杂志》
2010年第13期964-965,共2页
Journal of Clinical and Experimental Medicine
