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应用图像分析研究卵巢浆液性囊腺肿瘤形态学变化 被引量:3

Morphometric Study of Ovarian Serous Cystadenomatous Tumor
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摘要 目的:应用日本产Luzex-F型图像分析仪,对40例卵巢浆液性囊腺肿瘤与5例正常卵巢上皮组织进行了形态定量测定、比较分析,旨在探寻形态定量指标在鉴别诊断中的价值。方法:应用DNA特异染色(Feulgen染色),测量每例50~70个细胞核的面积、周长、最大直径、等效圆直径、核形状因子5项参数。经统计学分析。结果:上述各参数在各组之间具有非常显著性差异(P<0.01),交界性细胞核最大,恶性细胞核形状最不规则,良性细胞核较恶性小,但其形状较规则。结论:图像分析对卵巢浆液性囊腺肿瘤的病理学鉴别具有客观、正确的评价。 A respective morphometric analysis of surgically resected ovarian serous cystadenomatous tumors was performed with Luzex F image analysis system.Using Feulgen staining technique, 50 to 70 tumor cell nuclei were studied per case for their area, perimeter, maximum diameter, equivalent diameter and regular form factor. Highly significant statistical difference was observed in every parameter among normal, benign, borderline and malignant cases. We found that the borderline cell nucleus was the biggest, the malignant cell nucleus was most irregular in shape. It is suggested that morphometry can be used in differential diagnosis of benign, malignant and borderline tumor of ovary.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 1999年第1期45-47,共3页 Chinese Journal of Clinical Oncology
关键词 卵巢肿瘤 浆液性囊腺肿瘤 鉴别诊断 图像分析 Ovarian tumor Serous cystadenomatous tumor Morphometry Differential diagnosis
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