摘要
目的:探讨孟鲁司特联合布地奈德治疗支气管哮喘的临床效果。方法:选择我院2007年10月至2009年10月支气管哮喘103例,随机将上述患者分为两组,观察组和对照组。对照组患者给予博利康尼片2.5mg口服,每天3次,给予赛庚啶2.0mg口服,每天3次;观察组患者给予孟鲁司特片10mg,每天1次,睡前服用。同时给予布地奈德吸入200μg,每天2次。两组患者均治疗10天。在治疗期间观察两组患者哮喘发作次数;观察两组患者临床症状的缓解情况;定期对两组患者进行肺功能检查。结果:两组患者总有效率比较,差异有统计学意义(P<0.05)。观察组治疗后FEV1/FVC与对照组治疗后比较,差异有统计学意义(P<0.05);观察组治疗后PEF与对照组治疗后比较,差异有统计学意义(P<0.05)。结论:孟鲁司特联合布地奈德能够显著控制支气管哮喘急性发作症状,改善患者临床症状显著,提高患者肺功能,值得借鉴。
Objective：To discuss the clinical effect of budesonide combined with montelukast for the treatment of bronchial asthma.Method：103 cases with bron-chial asthma from Oct.2007 to Oct.2009 were ramdomly divided into observation group and control group.Control group was orally taken 2.5mg of bricanyl tablets and 2.0mg of cyproheptadine,three times a day.Observation group was orally taken 10mg of montelukast tablets before sleep,and 200μg of budesonide,twice a day.Both groups were treated for 10 days.The times of asthma attack and remission conditions were observed,and their lung function were regularly examined.Result：The differ-ence of two groups＇ total effective rates,FEV1 /FVC and PEF had statistical significance（P 0.05）.Conclusion：The combination of budesonide and montelukast can significantly control the symptoms of bronchial asthma attack,improve patients＇ clinical symptoms and lung funtion.It is worth of spreading.
出处
《医学信息（中旬刊）》
2010年第8期1976-1977,共2页
Medical Information Operations Sciences Fascicule
