摘要
目的分析急性百草枯中毒的临床特征。方法对45例急性百草枯中毒患者的临床资料进行回顾性分析。结果 45例患者中死亡28例(62.2%),治愈17例(37.8%);恶心、呕吐为最早出现的主要症状;气促为较晚出现的主要体征;死亡原因均为急性呼吸窘迫综合征(ARDS)、呼吸衰竭;血液净化可延缓肝损害的患者发生,但对肝损害的恢复无明显帮助;服毒量越大,死亡率越高,不同服毒量中毒死亡率差异有统计学意义(P<0.01);肺、肝、肾及多器官受损,死亡率明显增加。结论百草枯中毒可致多器官功能损害,预后差,早期综合治疗,可降低病死率。
[Objective]To analyze the clinical features of acute parapuat poisoning.[Methods]Retrospective analysis was performed on the clinical data of 45 cases of paraquat poisoning.[Results]Of 45 cases,28（62.2%）died,17 （37.8%）were cured; the major symptoms which appeared first were nausea and vomiting; shortness of breath was the late emergence of the main sign; the death causes were all acute respiratory distress syndrome and respiratory failure; blood purification could delay the occurrence of liver damage,but had no obvious help for liver damage recovery; the mortality was positively correlated with the amount of poison,the difference of mortality was significant between different amounts of poison（P0.01）; the multiple organ injuries of lung,liver and kidney on patients caused the increasing of mortality.[Conclusion]Paraquat poisoning can induce multiple organ dysfunction syndrome,and the prognosis was poor. The early comprehensive treatment can reduce mortality of patients with paraquat poisoning.
出处
《职业与健康》
CAS
2010年第13期1474-1475,共2页
Occupation and Health
关键词
百草枯
中毒
多器官损害
Paraquat
Poisoning
Multiple organ injury
