摘要
目的对我院5年来药物引起的471例胃肠道不良反应进行回顾性分析,为临床合理用药和预防胃肠道不良反应提供参考。方法对我院2005～2008年收集的471例胃肠道不良反应报表进行分类统计和分析。结果药品引发的胃肠道不良反应涉及201个品种,抗感染药居首位(218例,占46.28%),其次是中药制剂(88例,占18.68%);55岁以上的患者居多(占36.94%);口服给药引发胃肠道不良反应为257例(占54.57%)。结论临床应重视胃肠道不良反应的报告和致病原因,从而加强胃肠道不良反应的预防及监测,以减少和避免胃肠道不良反应的发生,保障患者用药合理、安全、有效。
Objective Over the past five years 471 patients drug-induced adverse drug reaction of gastrointestinal tract in our hospital were retrospectively analyzed to provide reference for the clinical reasonable medication and obviating adverse drug reaction of gastrointestinal tract.Methods 471 adverse drug reaction of gastrointestinal tract cases collected from 2005 to 2008 in our hospital were analyzed statistically.Results 471 adverse drug reaction of gastrointestinal tract cases refered to 201 kinds of drugs.Of which anti-infective agents occupied the first place which had 218 cases（46.28%）.Followed by the traditional Chinese medicine which had 88 cases（18.68%）.The majority of patients（36.94%） were over 55-years-old,and 257 cases（54.57%） were given orally.Conclusion Clinic should attach great importance to the reporting and principle and enhance to the obviating and detection of adverse drug reaction of gastrointestinal tract to reduce or avoid the occurrence of it,and to use reasonably safe and effective medications.
出处
《中国药物警戒》
2010年第7期435-438,共4页
Chinese Journal of Pharmacovigilance
关键词
胃肠道系统
药品不良反应
gastrointestinal tract system
adverse drug reaction（ADR）
