摘要
目的研究白介素６（ＩＬ－６）和可溶性白介素６受体（ｓＩＬ－６Ｒ）与低Ｔ３综合征的关系。方法根据血清总Ｔ３浓度将６４名患有各种非甲状腺系统急慢性疾病的入院患者分为Ａ组（Ｔ３＜０．８ｎｍｏｌＬ），即为低Ｔ３综合征组；Ｂ组Ｔ３正常（０．８～２．２ｎｍｏｌＬ）；Ｃ组即正常对照组。采用Ｅｌｉｓａ法测定３组的血清ＩＬ－６、ｓＩＬ－６Ｒ浓度。结果低Ｔ３组的ＩＬ－６水平比正常Ｔ３组、正常对照组明显升高，并随Ｔ３降低而升高，呈负相关关系。而Ｔ３正常组与正常对照组之间无显著差异。ｓＩＬ－６Ｒ值在３组中无明显差异。
Purpose To investigate the relationship between serum interleukin6(IL6),soluble interleukin6 receptor(sIL6R) levels and low T 3 syndrome. Methods Sixty four hospital admissions due to acute or chronic nonthyroidal illnesses were divided into subnormal T 3(T 3<0.80nmolL) group (group A, n =35);normal T 3 (T 3:0.80～2.2nmolL) group (group B, n =29)according to the measured serum total T 3(T 3)values.Control group (group C) is 19 healthy subjects.Serum IL6 and sIL6R were measured by Elisa assay inall subjects. Results Serum IL6 values in group A were higher than those in group B and C.The concentration of serum IL6 was negatively correlated to the level of serum T 3 in group A.Differences of serum sIL6R levels among the three groups were not significant. Conclusions [WT10.BZ〗These findings suggest that the development of low T 3 syndrome is related to the high level of serum IL6.
出处
《上海医科大学学报》
CSCD
1999年第1期48-50,共3页
Journal of Fudan University(Medical Science)
