摘要
目的探讨血清β2微球蛋白(β2-MG)和尿β2微球蛋白与2型糖尿病肾病的关系。方法采用免疫比浊法检测98例2型糖尿病患者和对照组38名健康者血清和尿β2-MG,在98例糖尿病患者中早期糖尿病肾病50例(DN组),糖尿病未出现肾损害48例(NDN组)。结果糖尿病肾病组血清和尿β2-MG与对照组之间差别均有统计学意义(P<0.01),糖尿病未出现肾损害组与对照组相比,血清β2微球蛋白差别没有统计学意义(P>0.05),尿β2微球蛋白差别具有统计学意义(P<0.05)。结论检测血清和尿β2微球蛋白早期诊断糖尿病肾病有良好的诊断价值。
Objective To explore the correlation between serumal and urinary β2-microglobulin（β2-MG） in patients with diabetic nephropathy.Methods Immunoturbidimetry was used to measure β2-MG in serum and urine from 98 patients with type 2 diabetes and 38 normal patients.Among 98 cases of diabetes,50 cases were diabetic nephropathy while the other 40 cases were not.Results Serumal and urinary β2-MG were significantly elevated in patients with diabetic nephropathy compared with those in normal patients（P0.01） No marked difference of serumal β2-MG was detected but significant differences of urinary β2-MG were found between non-nephropathy diabetes and normal persons（P0.05）.Conclusion Measuring serumal and urinary β2-MG is valuable to the diagnosis of diabetic nephropathy.
出处
《局解手术学杂志》
2010年第4期310-311,共2页
Journal of Regional Anatomy and Operative Surgery
关键词
Β2微球蛋白
糖尿病肾病
血清
尿
β2-microglobulin
diabetic nephropathy
serum
urine
