摘要
背景:目前国内外对非个体化假体的生物力学研究较多,而对个体化假体的生物力学资料尚缺乏。目的:探讨运用生物力学实验方法观测个体化假体生物力学的优越性。方法:①实验将经重建及快速成形制造的人个体化钛合金示指掌指关节标本设为个体化假体组;其对侧手标本的示指掌指关节为对照组;取5侧正常人手标本为正常对照组。在个体化假体组掌指关节植入个体化假体;对照组掌指关节植入Swanson假体。②利用CSS-44020试验机来模拟对3组标本分别以50,100,150,200,250,300,350N施加垂直载荷。③观察相应掌、指骨所受的应变变化,并绘制相应的载荷-应变曲线,观察和对比个体化假体、Swanson假体和正常掌指关节的生物力学特点。结果与结论:掌、指骨被垂直加压后,所受应变随着载荷加大而逐渐增大,观察各组数据,在实验测试范围内各应变片所测得应变值基本呈正态分布;掌骨在不同载荷下的应变要大于近节指骨。掌骨与近节指骨的应变变化在300～350N出现了"平台期"。在压力为50N时,各组掌、指骨所受的应变没有差别。大于100N时,对照组与个体化假体、正常对照组应变相比差异均有显著性意义,而个体化假体、正常对照组间应变差异无显著性意义。说明个体化钛合金假体更符合掌指关节的解剖学形状,也就更符合正常掌指关节的生物力学,因此个体化钛合金假体要优于Swanson假体,为临床提供了一种新型理想的掌指关节假体。
BACKGROUND： Studies have been conducted regarding biomechanics of non-individualized prosthesis. But biomechanical data ofindividualized metacarpophalangeal （MP） joint prosthesis are few.
OBJECTIVE： To explore the superiority of biomechanical characters to detect biomechanics ofindividualized prosthesis.
METHODS： The experimental specimens were divided into three groups. Individualized prosthesis group （MP joints were replaced by individualized titanium alloy prosthesis）, control group （MP joints were replaced by Swanson prosthesis） and normal group （normal human hand）. Every group was subjected to vertical loading of 50, 100, 150, 200, 250, 300, and 350 N by CSS-44020 machine. The strain changes of metacarpal and phalanx bone were observed and the loading-strain curves were drawn. The biomechanics ofindividualized Titanium alloy prosthesis, Swanson prosthesis and normal MP joints were analyzed and compared.
RESULTS AND CONCLUSION： The strain of metacarpal and proximal phalanx bones was increased with increasing loadings. The strain of each test displayed normal distribution. The strain changes of metacarpal bones were greater than proximal phalanx bones at different loading. They all had ＂platform＂ period at 300-350 N. No significant strain changes were observed in each group under 50 N loading. The straining changes of control group were significantly different from the other groups when the loading was larger than 100 N. But no differences were observed between individualized prosthesis and normal groups. Results show that individualized titanium alloy prosthesis well matched anatomy of MP joint, and displayed better biomechanics compared with Swanson prosthesis. It provides a novel ideal MP joint for clinical application.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2010年第26期4770-4773,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
基金
吉林省科技厅科技发展计划项目资助课题(20060414-1)~~
