摘要
目的:建立HPLC法测定消疲宁颗粒中丹参素钠含量的方法。方法:色谱柱为迪马C18(200mm×4.6mm),流动相为乙腈-水-醋酸(5:160:1),检测波长:281nm。结果:丹参素钠进样量在0.1148～1.0332μg范围内呈良好的线性关系,平均回收率为100.24%,RSD为1.23%。结论:方法快速准确,重复性好,准确度高,可控制制剂的质量。
Objective：To establish a method for determination of sodium danshensu in xiaopining granules by HPLC.Methods：Sodium danshensu content was determined on DiMa C18 Chromatographic column（200mm×4.6mm）,with mobile phase of acetonitrile-water-acetic acid（5：160：1）,Detected wavelength：281nm.Results：A good linear relationship was obtained when the detection concentration range was 0.1148～1.0332μg,and the average recovery is 100.24%,RSD is 1.23%.Conclusion：The method is fast and accurate,reproducible,high accuracy and the quality of preparation can be controlled.
出处
《辽宁中医药大学学报》
CAS
2010年第7期179-180,共2页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
消疲宁颗粒
含量测定
丹参素钠
Xiaopining granules
content determination
sodium danshensu
