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布托啡诺与芬太尼应用于术后静脉镇痛的临床观察 被引量:9

Comparison of Clinical Effect of Venous Analgesia between Butorphanol Tartrateand Fentanyl
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摘要 目的比较布托啡诺与芬太尼用于患者自控静脉镇痛(PCI)的临床价值。方法选择80例择期手术患者随机分为两组,N组(布托啡诺组:n=40):布托啡诺8mg、生理盐水加至100ml;F组(芬太尼组:n=40):芬太尼0.8mg、生理盐水加至100ml。选择负荷剂量加维持剂量即微泵连续给药方式行静脉镇痛(持续注药速度为2.0ml/h,单次PCA剂量为1ml,锁定时间30min)。结果 N组与F组相比,镇痛评分、镇静评分、恶心呕吐、尿潴留发生率均无显著差异性(P>0.05)。两组患者均无发生呼吸抑制。结论布托啡诺用于术后静脉镇痛,效果确切、不良反应少。 Objective To compare the effects of patient2controlled intravenous analgesia( PC I A) be- tw een butorphanol tartrate ( B T) and fentanyl. Methods Eghity patients were divided into t o group s at ran- dom. Group N was adm inistered with 8 mg of B T in 100 ml of saline, and Group F with 0. 8 rag of fentanyl in 100 ml of saline. The loading dosage and maintained do sage wereused as venous analgesia. Results There were no significant differences in visual ache sim ulation ( VA S) scoring, syrup tom s and urine retention be- tween B T and fentanyl without respiratory. Conclusion BT m ight be used as an analgetic agent after opera- tion with good effect.
作者 刘江洪
出处 《中国实用医药》 2010年第19期43-44,共2页 China Practical Medicine
关键词 术后静脉镇痛 布托啡诺 芬太尼 Postoperative intravenous analgesia Butorphanol tartrate Fentanyl
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参考文献3

  • 1江明性.药理学.人民卫生出版社,1989:134-140.
  • 2Vogelsang J, Hayes SR. Butorphanol tart rate (stadol) :a review. J Post Anest h Nurs,1991,6:129-135.
  • 3Chu CC, Cllen JY, Chen CS, et al. The efficacy and safety of tran2 snasal' butorphanol for postoperative pain cont rol follow ing lowerlaparoscop ic surgery. Acta A naest hesiol Taiw an, 2004, 42: 203 -207.

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