摘要
目的观察山东省肥城市食管癌高发区人群不同食管部位患病情况,为病因学研究提供科学依据。方法碘染色内镜检查食管黏膜,不染色区域取活检,经病理学诊断食管各种病变情况。结果普查有效资料9526人,取活检经病理诊断1418例,其中食管上段337例,上中交界63例,中段560例,中下交界64例,下段394例;发现食管上段、中段、下段食管癌分别为34,66,35例;将性别、年龄、文化水平、家庭人均收入作为调整因素,发现食管癌家族史、吸烟、饮酒对食管不同部位病变有不同程度的影响,其中对中段食管疾病的影响最为明显。结论食管中段是食管病变的好发部位,受各种危险因素的影响最大,需进一步研究不同部位食管癌的危险因素。
Objective To observe mucosa lesions of different sections of esophagus among residents at high-risk of esophageal cancer for aetiologic research.Methods Iodine-staining esophageal endoscope examination was conducted and the esophageal tissues with negative iodine-staine were pathologically examined.Results Among 9 526 participants,1 418 were pathologically examined.Biopsy samples were obtatined from upper section in 337 participants,upper-middle junction in 63,middle section in 560,middle-low junction in 64,and low section in 394,respectively.Overall 66,34 and 35 cases of esophageal cancer were found in upper,middle,and low sections,respectively.After adjustment of gender,age,education,average family income,the family history of esophaged cancer,smoking,and drinking were related to esophageal lesions of different sections,especially for middle esophagus section.Conclusion Middle section is the predilection site of esophageal diseases and is prone to being affected by different risk factors.It is necessary to make a thorough study on risk factors of esophageal cancer in different sections.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2010年第7期817-818,共2页
Chinese Journal of Public Health
基金
国家自然科学基金(30571601)
山东省2004年科学技术发展(重大专项部分)项目(2004GG1108039)
2007年度山东省博士后创新项目专项资金资助(200702034)
关键词
食管鳞癌
不典型增生
内窥镜检查
食管癌高发区
病变部位
esophageal squamous cell carcinoma
atypical hyperplasia
endoscopy
high-incidence area
lesion section
