摘要
目的探讨血清CA125、CA199联合超声检查对卵巢肿瘤的诊断价值。方法对152例卵巢肿瘤患者,其中恶性32例,良性120例,分别经腹及经阴道超声观察二维图像,并进行彩色及频谱多普勒检查,记录阻力指数,同时用放射免疫法测定血清CA125、CA199。分别对卵巢肿瘤进行良恶性的判定,并与术后病理结果进行对照。分别比较各种方法单检及联检诊断卵巢肿瘤的敏感性、特异性。结果血清CA125、CA199联合二维超声、彩色多普勒诊断卵巢肿瘤的敏感性、特异性高于任何单项检查方法。结论肿瘤标记物CA125、CA199联合超声的应用对卵巢肿瘤的诊断有一定价值。
Aim To investigate the diagnosis value of combined measurement of serum CA125 ,CA199 and Doppler ultrasound in patients with ovarian tumor. Methods 152 patients with ovarian tumors including 32 malignant tumors and 120 benign tumors were studied. Serum CA125, CA199 levels were measured by RIA. Meanwhile, the resistant index（RI） was detected by TBS and TVS . We selected different standards to judge the nature of the tumors and compared with pathological diagnosis after operation. The sensitivity and specificity for respective measurement and combined measurement were also compared in many methods of ovarian tumor diagnosis. Results The sensitivity and specificity of serum CA125 , CA199 and two-dimensional ultrasound, RI combined used were much higher than any one of others. Conclusions The combined use of CA125 , CA199 and two-dimensional ultrasound, RI may help for diagnosis of ovarian tumors.
出处
《安徽医药》
CAS
2010年第8期924-926,共3页
Anhui Medical and Pharmaceutical Journal
