摘要
巴马亭(又称黄藤素、非洲防己碱,palmatine,1),化学名为5,6-二氢-2,3,9,10-四甲氧基二苯并[a,g]喹嗪内鎓盐,具有广谱抗菌作用,临床上可用于治疗妇科炎症、菌痢、肠炎、呼吸道和泌尿道感染、外科感染及结膜炎等。
Bererine was treated with AlCl3 to give 5,6-dihydro-2,3,9,10-tetrahydroxy-dibenzo[a,g]-quinolizinium,which was subjected to methylation with dimethyl sulfate to provide palmatine in 54% overall yield.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2010年第7期494-495,共2页
Chinese Journal of Pharmaceuticals