摘要
目的探讨鲍氏不动杆菌(ABA)医院感染的分布及耐药现状,为临床医师诊断和治疗疾病提供科学依据。方法 256株ABA分离鉴定严格按《全国临床检验操作规程》进行;药敏试验采用K-B法,依据CLSI 2008-2009年折点判读结果。结果某院ABA分离率居前5位的临床科室依次为ICU占24.6%、脑外科15.6%、呼吸内科13.3%、肿瘤科12.0%、血液内科10.2%;ABA在呼吸道标本中检出率最高,达69.9%;ABA对16种常用抗菌药物均产生了不同程度的耐药性,ABA泛耐药菌株检出率为8.2%。结论应重视对多药耐药ABA的监测与控制,预防ABA医院感染暴发流行。
OBJECTIVE To investigate the clinical distribution and drug-resistance in nosocomial infections with Acinetobacter baumannii（ABA） and to provide the scientific evidence for clinical diagnosis and treatment.METHODS Referring to National Clinical Laboratory Operation Rules,256 strains of ABA were isolated and identified.The drug-sensitivity test was performed by K-B.The test results were read according to CLSI 2008-2009.RESULTS The top five isolated rates were 24.6% in the intensive care unit,15.6% in the deparment of neurosurgery,13.3% in the department of respiration,12.0% in the department of tumor and 10.2% in the department of hematology.The detection rate of ABA from specimen from respiratory tract was the highest,arriving at 69.9%.Drug sensitivity results showed ABA had been resistant to sixteen commonly used antibiotics in different degrees.The detected rate of pan-resistant strains was 8.2%.CONCLUSIONS Hospitals should attach importance to the monitoring and the controlling of multidrug-resistant ABA and prevent the outbreak and epidemic of nosocomial infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第14期2150-2151,共2页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
医院感染
临床分布
耐药性
Acinetobacter baumannii
Nosocomial infection
Clinical distribution
Drug-resistance
