摘要
观察176例慢性阻塞性肺病(COPD)不同临床分期的动脉血气分析资料在动脉血气图上的变化规律.结果显示:(1)急性发作期患者的动脉血气分布在通气不足合并换气损害区(5区)占52.8 %、通气代偿换气损害区(4区)占25.6 %和通气过度合并换气损害区(6区)占21.6%.5区病例的病死率最高,为23.7%,高于4区和6区(P<0.05).(2)出院时(临床缓解期)96例复查血气,4区58例,占60.4%,5区26例,占27.1%,6区9例,占9.4%,血气正常区(1区)3例,占3.1%,其中92例动脉氧分压大于8.0kPa.(3)死亡者死亡前血气均在5区.动脉血气图可直观反映COPD患者通气和/或换气功能的病理生理变化,为临床分期、治疗方法选择和预后判断提供帮助.
The changes of arterial blood gases parameters of 176 patients with chronic obstructive pulmonary disease (COPD) in the variant clinical staging on arterial blood gases graph( ABGG) were observed. The results showed: (1) In the acute attack phase, the distributions of the arterial blood gases parameters on ABGG were as follows:52.8% cases on the area of insufficient ventilation and damaged gases exchange(area 5),25.6% cases on the area of compensated ventilation and damaged gases exchange(area 4),21.6% cases on the area of excessive ventilation and damaged gases exchange(area 6).The mortality of the patients on the area 5 was 23.7% and higher than that on the area 4 and area 6(P<0.05). (2) In the period of remission, the distributions of the arterial blood gases parameters of 96 patients with COPD were as follows: on the area 4(60.4%),on the area 5(27.1%),on the area 6(9.4%),and on the normal area(3.1%). Among all cases, 92 cases (accounting for 95.8%) had arterial oxygen pressure values higher than 60mmHg. (3)Before death, the arterial blood gases parameter of fatal cases were exclusively on the area 5(PaO2 <60mmHg). It suggests that ABGG could directly reflect the patho - physiological change of ventilation and/or gases exchange function in COPD patients and it is useful in judgement of staging, selection of treatment and assessment of prognosis.
出处
《交通医学》
1999年第1期4-5,7,共3页
Medical Journal of Communications
