摘要
目的探讨甲型H1N1流感轻症与重症患者的临床特征、发病规律及治疗效果。方法对8例轻症、9例重症甲型H1N1流感住院患者的临床表现、辅助检查及转归进行分析。结果轻症患者多为流感样症状;白细胞降低或正常,中性粒细胞百分比降低,淋巴细胞百分比增高,单核细胞百分比正常;经治疗白细胞及中性粒细胞百分比恢复正常,单核细胞百分比于恢复期增高;肝功能无损伤;胸片、肺CT无异常或肺纹理增强、结节样影;治疗效果好。重症病例除流感样表现外,3～5天病情迅速发展,出现呼吸困难,需要入住重症监护病房,接受辅助通气;并出现白细胞、中性粒细胞百分比增高,淋巴细胞百分比降低;肝功能损伤;双肺多叶(中、下叶为主)实变影和周围毛玻璃样影;治疗效果差。结论通过临床表现、实验室检查等指标及早发现甲型H1N1流感重症病例,给予及时、有效治疗,减少并发症及死亡率。
Objective To discuss different clinical features of mild and severe cases of Type A H1N1 influenza.Methods The clinical features,examinations and prognosis of 8 mild cases and 9 severe cases of Type A H1N1 influenza were analyzed.Results Mild patients with Type A H1N1 influenza showed ＂flulike syndrome＂,with low or normal white blood cells and without liver damage.And their chest X-ray or lung CT remaind normal or increased lung markings,nodular shadow.Severe patients showed＂flu-like syndrome＂at early stage,and 3～5 days later their symptoms progressed rapidly.Then they were ac-commodated in intensive care unit because of dyspnea and given assisted ventilation.In severe patients the white blood cell and neutrophil percentage increased,accompanied with liver damage.The Chest X-ray or lung CT lungs showed multi-leaf,mainly middle and lower leaf-based,consolidation and the surrounding ground-glass opacities.Conclusion Compared with mild cases,severe patients have more severe clinical manifestation,laboratory examination and poorer therapeutic effect.Early diagnosis and early treatment would reduce complications and mortality.
出处
《哈尔滨医科大学学报》
CAS
北大核心
2010年第3期267-270,共4页
Journal of Harbin Medical University
关键词
甲型H1N1流感
肺炎
呼吸衰竭
机械通气
Type A H1N1 influenza
pneumonia
respiratory failure
mechanical ventilation
