摘要
通过对３７例肾移植术患者测定其手术前后唾液ｓＩｇＡ、溶菌酶的含量，同时观察手术前后口腔的病变情况，并与正常人进行了比较。结果发现唾液ｓＩｇＡ含量术前与正常人无差异，术后１周较术前升高，较正常人显著升高（Ｐ＜０．０５），术后２周较术后１周下降。术后发生口腔病变者为４１％。主要表现为口干、口腔溃疡、龈苍白及黑毛舌。其中口干组唾液ｓＩｇＡ含量较正常组与术前显著升高（Ｐ＜０．０５），黑毛舌组较术前与正常组下降。说明口腔病变是肾移植术后一种免疫性疾病。唾液溶菌酶的含量术前较正常人非常显著升高（Ｐ＜０．０１），术后１周较术前升高，术后２周较术后１周下降，较术前略下降，较正常人显著升高（Ｐ＜０．０５）。口干组及溃疡组较术前与正常人显著升高（Ｐ＜０．０５），其含量的变化与ｓＩｇＡ含量变化呈相关关系。
Measurements of sIgA and Lysozyme level in saliva were taken and situation of oral lesions observed preoperatively and postoperatively in 37 patients who receive kindney transplantation.There are 41% of all the postoperative patients developed oral lesions.The lesions include:dry mouth,oral mucous ulceration,ingival pale andhairy tongue.Compared with normal people and preoperative patients ,sIgA level of dry mouth group increased significantly( P <0.05),this level of hairy tongue group decreased.The result suggests that oral lesions are kinds of immune diseases after kidney trasplantation.Changes of sIgA level is a kind of immune response to maintain the integration of the body.Lysozyme as one of nonspecific immunity of the body,is of special meaming for renal patients.
出处
《临床口腔医学杂志》
1999年第1期19-20,共2页
Journal of Clinical Stomatology
