期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

含硅二烃基锡苯氧乙酸配合物的合成与结构表征 被引量：3

Synthesis and structure of diorganotin phenoxy acetic acid containing silicon
下载PDF
导出
摘要 Six diorganotin phenoxy acetic acid containing silicon were synthesized by the reaction of diorganotin oxides with phenoxy acetic acids;and their structures were characterized by IR,1HNMR,13CNMR,elemental analysis.The preliminary bioassay tests showed that(Me3SiCH2)2Sn(OCOCH2C6H4CH3-p)2 exhibited a good antitumour activity in vitro against lung tumour cells A549 and colorectal tumour cell SW480. Six diorganotin phenoxy acetic acid containing silicon were synthesized by the reaction of diorganotin oxides with phenoxy acetic acids;and their structures were characterized by IR,1HNMR,13CNMR,elemental analysis.The preliminary bioassay tests showed that（Me3SiCH2）2Sn（OCOCH2C6H4CH3-p）2 exhibited a good antitumour activity in vitro against lung tumour cells A549 and colorectal tumour cell SW480.
作者 林森 肖灵虎 江玉春 邓锋杰 揭克敏 邓检阳
机构地区 南昌大学化学系 南昌大学医学院
出处 《化学研究与应用》 CAS CSCD 北大核心 2010年第7期926-929,共4页 Chemical Research and Application
基金 国家自然科学基金(20762006)资助项目 江西省自然科学基金(2007JZH2103)资助项目
关键词 含硅二烃基锡化合物 苯氧乙酸 合成 结构 抗癌活性 diorganotin containing silicon phenoxy acetic acid synthesis structure antitumour activity
分类号 O627.41 [理学—有机化学]
  • 相关文献

参考文献13

二级参考文献40

共引文献65

同被引文献41

  • 1谢庆兰,林森,沙印林.三［（三甲硅基）亚甲基］锡芳香酸酯的研究[J].高等学校化学学报,1994,15(10):1477-1480. 被引量：23
  • 2杨志强,谢庆兰,周秀中.混合三烃基锡衍生物的研究（Ⅲ）──二丁基一环己基锡羧酸酯的合成、结构表征及生物活性[J].高等学校化学学报,1995,16(1):59-63. 被引量：9
  • 3林森,邓瑞红,卢志强,孙小强,汪信,陆路德.二(三甲硅亚甲基)锡二芳香羧酸酯的合成和结构表征[J].有机化学,2005,25(10):1298-1301. 被引量：14
  • 4Hadjikakou S K, Hadjiliadis N. Antipreliferative and antitumor activity of organotin compounds [ J ]. Coord. Chem. Rev. ,2009,253:235-249.
  • 5Baul T S B. Antimicrebial activity of organotin ( Ⅳ ) compounds : a review [ J ]. Appl. OrganometChem. , 2008,22 : 195-204.
  • 6Cecchetti V, Fravolini A, Pagella P G, et al. Quinolinecar- boxylic acids. 3. synthesis and antibacterial evaluation of 2-substituted-7-oxo-2,3-dihydre-TH-pyrid [ 1,2,3-de ] [ 1, 4] benzotiazine-6-carboxylic acids related to nffloxacin [ J]. J. Med. Chem. , 1993,36:3449-3454.
  • 7Epstein J W, Brabander H J, Fanshawe W J, et. al. l-Aryl- 3-azabieyclo[ 3.1. O] hexanes, a new series of nonnarcotic analgesic agents[J]. J. Med. Chem. ,1981,24:481-490.
  • 8Dornfeld C A. 2-Aryloxyaralkyl-1,4,5,6-tetrahydropyrimidines[ P]. US :2893993,1959-07-07.
  • 9Jesper L, Tibor K J, Mustafa G, et al. Preparation of N-aryl amide derivatives as g]ucokinase(GK) activators[ P]. WO: 2003055482,2003 -07 -10.
  • 10Szoresik A, Nagy L, Sletten J, et. al. Preparation and structural studies on dibutyhin(IV) complexes with pyridine mono-and dicarboxylic acids [ J ]. J. Organomet. Chem. ,2004,689 : 1145o1154.

引证文献3

化学研究与应用
2010年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部