卵泡未破裂黄素化综合征58例临床治疗被引量：3

Clinical analysis of 58 cases of luteinized unruptured follicle syndrome

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摘要目的探讨多囊卵巢综合征(PCOS)促排卵治疗中出现的卵泡未破裂黄素化综合征(LUFS)的治疗措施。方法选择2006年1月～2007年12月在临沂市妇幼保健院生殖中心就诊的PCOS不孕症患者经促排卵治疗,对发生LUFS 58例患者35例给予卵泡穿刺(为穿刺组),23例妇科检查机械性挤压法(为挤压法组)治疗,比较治疗后的排卵率、妊娠率以及中、重度卵巢过度刺激综合征(OHSS)的发生率。结果穿刺组排卵率为100%(35/35),妊娠率为31.4%(11/35),OHSS的发生率为2.9%(1/35);挤压组排卵率为47.8%(11/23),妊娠率为8.7%(2/23),OHSS的发生率为13.0%(3/23);两组妊娠率及OHSS发生率比较,差异无统计学意义;穿刺组排卵率高于挤压组,差异有统计学意义(P<0.001)。结论PCOS促排卵治疗中发生的LUFS给予卵泡穿刺术治疗效果肯定,是一种有效的治疗方法。 Objective To evaluate the treatment of luteinized unruptured follicle syndrome （LUFS） in patients with polyeystic ovary syndrome （PCOS） in ovulation induction. Methods Fifty-eight LUFS patients with PCOS in ovulation induction were analyzed. All patients were divided into two groups. 35 eases （ Group 1 ） were underwent ultrasound-directed follicular aspirations and 23 cases（ Group 2 ） were give gynecological examination with mechanical extruding. Results All 35 cases in group I were successful in ovulation induction. Eleven pregnancies and one moderate ovarian hyperstimulation syndrome （OHSS） occurred in group 1, resulting in a pregnancy rate of 31.4 %, and an incidence of moderate OHSS 2. 9 %. Two pregnancies and 11 ovulation induction developed in group 2 with 3 moderate OHSS, resulting in a pregnancy rate of 8.7 %, an incidence of ovulation 47. 8 %, and an incidence of moderate OHSS 13.0 %. No severe cases of OHSS were noted in either of the two groups. Comparison of the therapeutic effects between the two groups showed significant difference （ P 〈 0. 001 ）, with higher incidence of ovulation in group 1 than in group 2. No significant differences were noted in pregnancy rate and incidence of moderate OHSS （ P 〉 0. 05 ）. Conclusion The therapy of ultrasound-directed follicular aspirations is effective in treating LUFS with PCOS in ovulation induction.

作者王新民

机构地区临沂市妇幼保健院生殖中心

出处《中国生育健康杂志》 2010年第3期155-157,160,共4页 Chinese Journal of Reproductive Health

关键词多囊卵巢综合征卵泡未破裂黄素化综合征不孕症卵泡穿刺妇科检查机械性挤压 Polyeystic ovary syndrome Luteinized unruptured follicle syndrome Infertility Follicular aspiration Gynecological examination with mechanical extruding

分类号 R711.75 [医药卫生—妇产科学]

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