摘要
目的探讨高频重复经颅磁刺激（rTMS）对脑卒中后抑郁（PSD）的临床治疗作用。方法将60例PSD患者随机分为rTMS组和对照组各30例，在常规治疗基础上，rTMS组给予高频rTMS治疗，对照组给予假刺激，治疗10d。于磁刺激治疗前、治疗结束当日及治疗结束30d后分别采用汉密尔顿抑郁量表（HAMD）对2组患者进行评分。结果治疗结束当日，rTMS组的HAMD评分显著低于治疗前（P〈0．01），与对照组的HAMD评分比较，差异具有统计学意义（P〈0．01）；rTMS组的有效率显著高于对照组（P〈0．01）。治疗结束30d后，对照组的的HAMD评分显著低于治疗结束当日（P〈0．01），2组HAMD评分和有效率比较，差异均无统计学意义（P〉0．05）。结论高频rTMS辅助治疗PSD是安全有效的。
Objective To explore the clinical effect of high-frequency repetitive transcranial magnetic stimulation （rTMS） on post-stroke depression （PSD）. Methods Sixty PSD patients were randomly divided into an rTMS group and a control group, each of 30 patients. In addition to conventional treatment, rTMS group members were given high-frequency rTMS treatment for 10 d while the control group were given sham stimulation. In order to test the efficacy, the two groups were compared using the Hamilton depression rating scale （HAMD） before and after 10 and 30 days treatment. Results After 10 days of treatment the rTMS group had significantly lower HAMD scores than before treatment, and average HAMD scores differed significantly between the rTMS group and the controls, with the former performing significantly better. There was no obvious difference in HAMD scores after 30 days of treatment between the two groups. Conclusions High-frequency rTMS is a safe and effective treatment for PSD.
出处
《中华物理医学与康复杂志》
CAS
CSCD
北大核心
2010年第7期513-515,共3页
Chinese Journal of Physical Medicine and Rehabilitation
关键词
重复经颅磁刺激
脑卒中后抑郁
汉密尔顿抑郁量表
Repetitive transcranial magnetic stimulation
Post-stroke depression
Hamilton depression rating scale
