摘要
目的：研究旋覆花地上部分中的化学成分。方法：应用硅胶柱色谱,SephadexLH-20柱色谱,以及高效液相制备色谱等手段分离和纯化化合物,通过光谱学方法,并结合化合物的理化性质鉴定它们的结构。结果：从旋覆花地上部分中分离得到9个黄酮类化合物,分别鉴定为槲皮素（1）、5,7-二羟基-3,3＇,4＇-三甲氧基黄酮（2）、3,5,7,4＇-四羟基-3’,6-二甲氧基黄酮（3）、5,7,3＇,4＇-四羟基-3,6-二甲氧基黄酮（4）、异泽兰黄素（5）、紫花牡荆素（6）、芹菜素（7）、木犀草素（8）、黄芩素（9）。结论：化合物2、6、和9为首次从旋覆花属中分得,化合物3~5为首次从该旋覆花中分离得到。
AIM：To investigate the chemical constituents of the aerial parts of Inula japonica Thunb..METHODS：Compounds were isolated and purified by column chromatography with silica gel,Sephadex LH-20 and preparative HPLC.Their structures were identified on the basis of physicochemical properties and spectroscopic data.RESULTS：Nine flavonoids were isolated and elucidated as quercetin（1）,5,7-dihydroxy-3,3＇,4＇-trimethoxyflavone（2）,spinacetin（3）,axillarin（4）,eupatin（5）,casticine（6）,apigenin（7）,luteolin（8）,and 6-hydroxyapigenin（9）.CONCLUSION：Compounds 2,6 and 9 were isolated from this genus for the first time,and compounds 3-5 were isolated from this plant for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2010年第4期257-259,共3页
基金
supported by Scientific Foundation of Shanghai China (No. 08DZ1971302)~~
