摘要
目的:观察甲基泼尼松龙(MP)冲击联合氮芥治疗狼疮性肾炎过程中的副作用,探讨有效的护理方式。方法:对收治的103例狼疮性肾炎(LN),进行甲基泼尼松龙冲击联合氮芥治疗,在加强心理护理,预防和控制感染及针对药物不良反应的特殊护理的基础上,观察该疗法的副作用。结果:氮芥的消化系统反应79例(76.70%),脱发1例(0.97%),骨髓抑制31例(30.10%),出血性膀胱炎0例,停经1例(0.97%),全身感染4例(3.88%)。结论:严格掌握氮芥的适应证,积极做好并发症的预防预案,正确使用氮芥的注射方法,认真观察、积极处置其副作用,进行合理有效的护理,甲基泼尼松龙冲击联合氮芥治疗狼疮性肾炎是安全、有效的。
Objective： To examine the side-effect of methyl prednisolone（MP） pulse therapy combined with mustard nitrogen in treating lupus nephritis （LN） and explore the effective nursing methods. Methods： Applied methyl prednisolone pulse therapy combined with mustard nitrogen as the major treatment to 103 cases with lupus nephritis strengthening mental nursing and special care in order to prevent and control infections and untoward effects of the medication, on the bases of the side-effects of this treatment and compared with the untoward effects of using cyclophosphamide to treat nephritic diseases. Results： Digestive system reactions of mustard nitrogen were 79 cases （76.70%）, 1 case（0.97%）with alopecia, 31 cases （30.10%）with myelosuppression, no hemorrhagic cystitis, 1 case（0.97%）with menolipsis, 4 cases（3.88%） with systemic infection. Conclusion： Strict control indication of mustard nitrogen, prevent complications positively, inject the mustard nitrogen in the right method,keep a close eye on the side-effects and handle them properly, and provide effective nursing to the patients, this treatment can be safe and effective in treating the lupus nephritis.
出处
《中国当代医药》
2010年第21期123-124,共2页
China Modern Medicine
关键词
甲基泼尼松龙
氮芥
狼疮性肾炎
护理
Methyl prednisolone
Mustard nitrogen
Lupus nephritis
Nursing
