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托特罗定治疗良性前列腺增生切除术后膀胱痉挛疗效观察 被引量:4

Observation on the clinic efficiency of tolterodine for the treatment of spasm of bladder after the resection of benign prostata hyperplasia
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摘要 目的:托特罗定治疗良性前列腺增生切除术后膀胱痉挛疗效观。方法:术前3~5d和术后4~5d口服托特罗定2mg,每日2次。结果:168例患者中,未发生痉挛者141例,轻度痉挛22例,重度痉挛5例,无严重不良反应。结论:托特罗定在防治良性前列腺增生术后膀胱痉挛中疗效满意,利于患者的恢复,是防治良性前列腺增生术后膀胱痉挛的有效药物。 OBJECTIVE To study the therapeutic effect of tolterodine on spasm of bladder after resection of benign prostata hyperplasia(BPH). METHODS Tolterodine 2 mg was given orally two times per day, 3-5 days before operation and 4-5 days after operation. RESULTS It was found 141 patients without spasm in the total cases of 168; 22 patients with mild spasm and 5 patients with severe spasm. All patients showed without severe side effects. CONCLUSION Tolterodine is an effective drug for the treatment of spasm of bladder after the resection of benign prostata hyperplasia.
机构地区 兰溪市人民医院
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2010年第14期1219-1220,共2页 Chinese Journal of Hospital Pharmacy
关键词 良性前列腺增生 托特罗定 膀胱痉挛 benign pros tata hyperplasia tolterodine bladder spasm
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  • 2Patrick CW, Alan BRE, Darracott V, et al. Pharmacology of the bladder and peripheral autonomic ganglia//Walsh PC, Retik AB, Stamey TA, et al. Campbell's urology. 7th ed. Philadelphia:Saunders, 1998:880 -889.
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  • 4Kanofsky JK, Nitti VW. Tolterodine for treatment of overactive bladder. Urol Clin North Am, 2006,33 : 447-453.
  • 5Mitropolos D, Papadoukakis S, Zervas A, et al. Efficacy of tolterodine in preventing urge incontinence immediately after prostatectomy. Int Urol Nephrol,2006,38 : 263-268.
  • 6吴士良,杨勇,薛兆英,那彦群,宋波,金锡御,丁强,张元芳,郭应禄.新型抗胆碱能药物托特罗定治疗膀胱过度活动症的临床研究[J].中华泌尿外科杂志,2001,22(4):217-219. 被引量:91

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