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肝硬化患者血清甲状腺激素检测的临床意义 被引量:3

Clinical Significance of Detecting Thyroid Hormone on Patients with Hepatic Cirrhosis
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摘要 目的:观察肝硬化患者血清甲状腺素表达变化,探讨其临床意义。方法:60名肝硬化患者,按照肝功能Child pugh分级分为A级组、B级组、C级组,检测各组患者血清TSH、FT_3、FT_4血清水平。结果:C组患者血清FT_3、FT_4表达水平低于A级组,TSH表达水平三组间无差异。结论:TSH、FT_3、FT_4表达水平变化能够反映肝硬化患者的肝功能状态,有助于评估病情及预后。 Objective:To observe expressive change of thyroid hormone on patients with hepatic cirrhosis and investigate the clinical significance.Methods:60 cases of patients with hepatic were divided into A groups,Bgroups and Cgroups according to Child pugh grade of liver function, concentration of thyrotropic-stimulating hormone(TSH), free triiodothyronine(FT3) and free thyroxin in serum were detected. Results:In comparison with Agroups, concentration of FT3 and FT4 were lower in C groups, concentration of was identical among theer groups.Conclusions:Change in concentration of TSH,FT3 and FT4 could reflect liver function on patients with hepatic cirrhosis,and was heipful to evaluate pathogenetic condition and prognosis.
作者 钟伟
出处 《中国医药导刊》 2010年第6期1026-1027,共2页 Chinese Journal of Medicinal Guide
关键词 肝硬化 甲状腺激素 肝功能 预后 Hepatic cirrhosis Thyroid hormone Liver function Prognosis
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参考文献5

  • 1Zietz B,Lock G,Plach B,et al.Dysfunction of the hypothalamic-Pituitary-glandular axes and relation to Child-Pugh classification in male patients with alcoholic and virus relatcdcirrbosis[J].Eur J Gastroenterol Hepatol,2003;15(5):495-501.
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  • 4肖洪广,黄泽红,林勇平,陈柏铭.肝脏疾病对血清甲状腺激素水平的影响及其临床意义[J].广州医药,2005,36(1):68-69. 被引量:11
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