摘要
目的报道手术治疗骨转移癌的临床经验。方法１９８８年２月－１９９７年３月共手术治疗骨转移癌８９例。其中男５８例，女３１例。年龄１０－７４岁，其中４１－７０岁７２例，占８０．９％。其最好发部位分别是脊柱２３例，股骨２２例和骨盆１３例，而最常见的原发肿瘤分别是肺癌２２例，肝癌１１例。手术可分止痛、稳定瘤骨和肿瘤切除三大类。结果８９例中，７７例（８６．５２％）疼痛缓解或消失。７３例获随访（１－９年），１例术后３天死亡，术后３个月内死亡６例，４－６个月死亡７例，７－９个月死亡１２例，１０－１２个月死亡１８例，１－２年死亡１５例，５例２年以后死亡，至今存活９例，其中１例甲状腺癌脊柱转移者已存活６年。结论 骨转移癌手术的目的是缓解疼痛、改善生存质量和在可能情况下延长生命，而骨转移癌患者的生存时间主要与原发癌的组织学特征有关而与手术本身关系不大。
Objective To report the clinical experience of surgical treatment of metastatic careinomaof bone. methods From February 1988 to March 1997, 89 patients with metastatic carcinoma of bones wereoperated upon. There were 58 males and 31 femals, aged ranged from 10 to 70 years. Seventy-two cases agedbetween 41 and 70 years. The most frequent sites of bone metastases were the vertebrae (23 cases), femur(22cases) and pelvis ( 13 cases) . The lungs (22 cases) and liver carcinoma( 11 cases) were the most commonprimary tumors. The operations could be divided into 3 types: 1) for the alleviation of pain, 2) for therestoration of tumor bone stability and 3) for resection of tumor. Results Among 89 cases, 77 Patients(86. 52% ) had good relief of pain. Seventy-three were available for follow-up study. One patients died at thethird day after operation , 6 died during 3 months after operation, 7 died between 4 and 6 months, 12 diedbetween 7 and 9 months, 18 died between 10 and 12 months , 15 died between 1 and 2 years, 5 died beyond2 years, 9 patients are still alive, the duration of survival of one patient who had vertebral metastatic thyroidcarcinoma has been 6 years. Conclusions The aims of operation are to relieve pain, improve mobility andfunction, and if possible, prolong survival. However, the duration of survival mainly depends on the histo-logical characteristics of the primary carcinoma and the stage of the tumors rather than the operation itself
出处
《中华骨科杂志》
CAS
CSCD
北大核心
1999年第1期24-27,共4页
Chinese Journal of Orthopaedics
关键词
肿瘤转移
外科手术
预后
骨转移肿瘤
Neoplasm metastasis Bones Surgery, operative Prognosis
