期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

米非司酮配伍甲基睾丸素治疗围绝经期功血的体会 被引量：8

下载PDF
导出
摘要 目的探讨米非司酮配伍甲基睾丸素治疗围绝经期功血的疗效。方法对32例围绝经期功血患者,每天口服米非司酮12.5mg加甲基睾丸素5mg,连服3个月,随访观察月经恢复情况及治疗效果。结果所有患者用药期间均引起闭经、贫血得到改善;停药后月经复潮,可使经量减少,经期缩短;部分围绝经期妇女用药后进入绝经期。结论米非司酮配伍甲基睾丸素是治疗围绝经期功血的一种有效方法 。
作者 朱丽英 张艳平
机构地区 广东省连州市人民医院妇产科
出处 《中国现代药物应用》 2010年第15期122-123,共2页 Chinese Journal of Modern Drug Application
关键词 米非司酮 甲基睾丸素 围绝经期
分类号 R711.5 [医药卫生—妇产科学]
  • 相关文献

参考文献3

二级参考文献12

  • 1卫生部继续医学教育委员会.女性生殖内分泌性激素补充疗法[M].北京:北京医科大学、中国协和医科大学联合出版社,1999.84-90.
  • 2葛秦生 见:葛秦生 连利娟主编.功能失调性子宫出血[A].见:葛秦生,连利娟主编.生殖内分泌与妇产科疾病诊治手册[C].北京:中国协和医科大学出版社,2002.409-410.
  • 3Yamaguchi K,Kinosaki M,Goto M,et al.Characterization of structural domain of human osteoclastogenesis inhibitory factor〔J〕[].Journal of Biological Chemistry.1998
  • 4Tsuda E,Goto M,Mochizuki S,et al.Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis〔J〕[].Biochemical and Biophysical Research Communications.1997
  • 5Morinaga T,Nakagawa N,Yasuda H,et al.Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis-inhibitory factor〔J〕[].European Journal of Biochemistry.1998
  • 6Lacey DL,Timms E,Tan TL,et al.Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation〔J〕[].Cell.1998
  • 7Brandstrom H,Jonsson KB,Ohlsson C,et al.Regulation of osteoprotegerin mRNA levels by prostaglandin E2 in human bone marrow stroma cells 〔J〕[].Biochemical and Biophysical Research Communications.1998
  • 8Takai H,Kanematsu M,Yano K,et al.Transforming growth factor-beta stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells〔J〕[].Journal of Biological Chemistry.1998
  • 9Yasuda H,Shima N,Nakagawa N,et al.Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL〔J〕[].Proceedings of the National Academy of Sciences of the United States of America.1998
  • 10Hofbauer LC,Dunstan CR,Spelsberg TC,et al.Osteoprotegerin production by human osteoblast lineage cells in stimulated by vitamin D, bone morphogenetic protein-2, and cytokines 〔J〕[].Biochemical and Biophysical Research Communications.1998

共引文献54

同被引文献49

  • 1孙爱军.功能失调性子宫出血的性激素治疗[J].中国实用妇科与产科杂志,2006,22(9):650-652. 被引量：84
  • 2李瑛,陈峰,沈洪兵.低剂量复方口服避孕药与心血管疾病关系的研究进展[J].中国计划生育学杂志,2007,15(5):318-320. 被引量：7
  • 3乐杰主编.妇产科学[M].第6版.北京:人民卫生出版社,2003.141～142.
  • 4Baird DT, Brown A, Crithley HO, et al. Effect of long-term treatment with low-dose mifepristone on the endomefium. Hum Reprod,2003,18( 1 ) :61-68.
  • 5Sanchez Cfiado JE;Bellido C,Aguilar R,et al. Antiprogestin RU486 blunts the stimulatory effect of galanin on LH secretion from rat pituitaries in vito in an estrous cycle stagedependent manner. Neurosci Lett ,2009,305 ( 1 ) :73-75.
  • 6Vij U, Kumar A, Sharma K, et al. Effect of mifepristone on steroid receptor expression and biotransformation of oestrogen and progesterone in rat uterus and deeiduoma. Natl Med J India, 2008,19 (2) :64-69.
  • 7Chwalisz K, Brenner RM, Fuhrmann UU, et al. Antiproliferative effects of progesterone antagonists and progesterone receptor modulators on the endometrium review. Steroids, 2010,65 ( 10-11 ) : 741-751.
  • 8Murphy AA,Zhou MH,Malkapuram S ,et al. RU 486-induced growth inhibition of human endometrial cells. Fertil Steril, 2008,74 ( 5 ) : 1014-1019.
  • 9Seth S,Goel N,Singh E,et al.Effect of mifepristone(25mg)in treatment of uterine myoma in perimenopausal woman[J].J Midlife Heahh,2013,4(1):22-26.
  • 10Momoeda M,Harada T,Terakawa N,et al.Long-term use of dienogest for the treatment of endometriosis[J].J Obstet Gynaecol Res,2009,35(6):1069.

引证文献8

二级引证文献35

中国现代药物应用
2010年 第15期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部