摘要
目的探讨氯吡格雷治疗不稳定型心绞痛的临床疗效和安全性,提高患者的生存质量。方法将100例不稳定型心绞痛患者随机分为观察组50例和对照组50例,对照组给予皮下注射低分子肝素钙、口服阿司匹林肠溶片和安慰剂,观察组给予皮下注射低分子肝素钙、口服阿司匹林肠溶片和氯吡格雷片,比较患者的心绞痛和心电图疗效及不良反应等。结果观察组患者在心绞痛有效控制率和心电图改善情况,均明显好于对照组,差异有统计学意义(P<0.05);两组患者均未见明显不良反应发生。结论氯吡格雷治疗不稳定型心绞痛临床效果好,安全性高,值得临床应用推广应用。
Objective To discuss treatment efficacy and safety of unstable angina pectoris with plavix,and improve patients’ quality of Life.Methods 100 unstable angina pectoris patients were divided randomly into observation group（50 eases） and control group（50 cases）.The control group was treated with heparin,enteric-coated aspirin tablets and Placebo,the observation group was treated with heparin,enteric-coated aspirin tablets and plavix.Angina,ECG and adverse reactions in each group was observed.Results The angina pectoris patients in the control of heart rate and ECG improvement in observation group were better than the control group,with a significant difference between the two groups（P 〈0.05）.Patients in both groups have no significant adverse events.Conclusion The therapy effects of plavix in treating unstable angina pectoris were valid and safe.It is worthy of clinical application.
出处
《湖南中医药大学学报》
CAS
2010年第8期29-31,共3页
Journal of Hunan University of Chinese Medicine
