摘要
目的了解东莞地区泌尿生殖道解脲脲原体(UU)感染状况及其对抗生素的耐药情况。方法以微量肉汤稀释法做UU鉴定并做14种抗生素的敏感性实验。结果 1552例解脲脲原体培养阳性(41.28%),女性阳性率高于男性(P<0.01);药敏试验显示,UU对14种抗生素有不同程度的耐药,其中对红霉素、四环素、司帕沙星、环丙沙星、氧氟沙星、壮观霉素、罗红霉素、可乐比妥、乙酰螺旋霉素耐药率较高,且出现少数全部抗生素耐药病例;但其对交沙霉素、强力霉素显示出较高敏感性。结论重视性传播疾病(STD)门诊UU的培养与药敏实验,对指导临床用药、控制其传播、防止耐药性产生具有重要的意义。
Objective To investigate the status of ureaplasma urealyticum infection and antibiotic resistmace and then guide rational drug use in Dongguan area. Methods The micro - broth dilution and 14 kinds of antibiotics sensitivity test were used to determine the infection rate mad antibiotic resistance of ureaplasma urealytieum. Results The positivity of 1552 samples from 3760 samples for ureaplasma urealyticum culture was comfirmed （41. 28% ）. The detection rate of ureaplasma urealyticum in women was higher than that in men （ P 〈 0.01 ）. Antibiotics sensitivity test showed that remarkable resistance to erythromycin, tetracycline, sparfloxacin, eiprufloxacin, ofloxaein, speetinomyein, roxithromycin, levofloxacin, aeetyl spiramyein. Some cases were resistant to all the anti- biotics; meanwhile they showed higher sensitivity to josamycin, doxycycline. Conclusion It is important to cultivate and test the antibiotics sensitivity of ureaplasma urealyticum in the samples from the STD patients in order to guide the selection of antibiotics clinieally, control its spread and prevent the occurrence of antibiotics resistance.
出处
《海南医学》
CAS
2010年第15期94-95,共2页
Hainan Medical Journal
关键词
解脲脲原体
药敏试验
抗生素耐药性
Ureaplasma urealytieum
Antibiotics sensitivity test
Antibiotic resistance
