摘要
硫辛酸(α-lipoic acid,α-LA)是一种在酵母、菠菜及肉类中发现的生物因子,其主要生物活性是抗氧化,是目前已知的唯一具备脂、水兼容性的抗氧化剂。近年来,硫辛酸在抗氧化及治疗糖代谢、糖尿病并发症和其他多种疾病方面的作用已受到关注,其医用价值正在得到认可。现就硫辛酸在重要脏器缺血再灌注损伤保护作用的研究进行综述。
Lipoic acid（α-lipoic acid,α-LA） is a kind of biological factors found in yeast,spinach and meat,with the main biological activity of anti-oxidation,and is only known aqueous and lipid-compatible antioxidant.In recent years,the therapeutic effects of lipoic acid in anti-oxidation,glucose metabolism,diabetic complications,and other disease had drawn attentions and its medical value has been recognized.And progresses in the study protective effects of lipoic acid against ischemia-reperfusion injury in major organs are reviewed in the paper.
出处
《广东药学院学报》
CAS
2010年第3期326-329,共4页
Academic Journal of Guangdong College of Pharmacy
关键词
硫辛酸
脏器
缺血再灌注
保护作用
lipoic acid
organs
ischemia-reperfusion
protective effects
